Browse by RVC Staff

Up a level
Export as [feed] Atom [feed] RSS
Group by: Item Type | No Grouping
Number of items: 27.

Article

Poulet, B and De Souza, R and Kent, A V and Saxon, L K and Barker, O and Wilson, A M and Chang, Y M and Cake, M and Pitsillides, A A (2015) Intermittent applied mechanical loading induces subchondral bone thickening that may be intensified locally by contiguous articular cartilage lesions. OSTEOARTHRITIS AND CARTILAGE, 23 (6). pp. 940-948.

Windahl, S H and Saxon, L K and Borjesson, A E and Lagerquist, M K and Frenkel, B and Henning, P and Lerner, U H and Galea, G L and Meakin, L B and Engdahl, C and Sjogren, K and Antal, M C and Krust, A and Chambon, P and Lanyon, L E and Price, J S and Ohlsson, C (2013) Estrogen Receptor-alpha Is Required for the Osteogenic Response to Mechanical Loading in a Ligand-Independent Manner Involving Its Activation Function 1 but Not 2. JOURNAL OF BONE AND MINERAL RESEARCH, 28 (2). pp. 291-301.

Poulet, B and de Souza, R and Kent, A V and Saxon, L K and Barker, O and Wilson, A M and Chang, Y M and Cake, M and Pitsillides, A A (2013) THICKENING OF SUBCHONDRAL BONE IS REGIONALISED BY LOADING OF DAMAGED ARTICULAR CARTILAGE AND CONTRA-LATERAL CHANGES ARE LINKED TO GAIT MODIFICATION. OSTEOARTHRITIS AND CARTILAGE, 21. S68-S68.

Saxon, L K and Galea, G L and Meakin, L B and Price, J S and Lanyon, L E (2012) Estrogen Receptors alpha and beta Have Different Gender-Dependent Effects on the Adaptive Responses to Load Bearing in Cancellous and Cortical Bone. Endocrinology, 153 (5). pp. 2254-2266.

Zaman, G and Sunters, A and Galea, G L and Javaheri, B and Saxon, L K and Moustafa, A and Armstrong, V J and Price, J S and Lanyon, L E (2012) Loading-related Regulation of Transcription Factor EGR2/Krox-20 in Bone Cells Is ERK1/2 Protein-mediated and Prostaglandin, Wnt Signaling Pathway-, and Insulin-like Growth Factor-I Axis-dependent. JOURNAL OF BIOLOGICAL CHEMISTRY, 287 (6). pp. 3946-3962.

Zaman, G and Sunters, A and Galea, G L and Javaheri, B and Saxon, L K and Moustafa, A and Armstrong, V J and Price, J S and Lanyon, L E (2012) Loading-related regulation of the transcription factor EGR2/Krox-20 in bone cells is ERK 1/2 mediated and prostaglandin Wnt and IGF-I axis dependent. JOURNAL OF BIOLOGICAL CHEMISTRY, 287 (6). pp. 3946-3962.

Javaheri, B and Sunters, A and Zaman, G and Suswillo, R F L and Saxon, L K and Lanyon, L E and Price, J S (2012) Lrp5 Is Not Required for the Proliferative Response of Osteoblasts to Strain but Regulates Proliferation and Apoptosis in a Cell Autonomous Manner. PLoS One, 7 (5). e35726.

Saxon, L K and Jackson, B F and Sugiyama, T and Lanyon, L E and Price, J S (2011) Analysis of multiple bone responses to graded strains above functional levels, and to disuse, in mice in vivo show that the human Lrp5 G171V High Bone Mass mutation increases the osteogenic response to loading but that lack of Lrp5 activity reduces it. BONE, 49 (2). pp. 184-193.

Ducher, G and Bass, S L and Saxon, L K and Daly, R M (2011) Effects of Repetitive Loading on the Growth-Induced Changes in Bone Mass and Cortical Bone Geometry: A 12-Month Study in Pre/Peri- and Postmenarcheal Tennis Players. JOURNAL OF BONE AND MINERAL RESEARCH, 26 (6). pp. 1321-1329.

Zaman, G and Saxon, L K and Sunters, A and Hilton, H and Underhill, P and Williams, D and Price, J S and Lanyon, L E (2010) Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor alpha and disuse. BONE, 46 (3). pp. 628-642.

Rawlinson, S C F and Murray, D H and Mosley, J R and Wright, C D P and Bredl, J C and Saxon, L K and Loveridge, N and Leterrier, C and Constantin, P and Farquharson, C and Pitsillides, A A (2009) Genetic selection for fast growth generates bone architecture characterised by enhanced periosteal expansion and limited consolidation of the cortices but a diminution in the early responses to mechanical loading. BONE, 45 (2). pp. 357-366.

Moustafa, A and Sugiyama, T and Saxon, L K and Zaman, G and Sunters, A and Armstrong, V J and Javaheri, B and Lanyon, L E and Price, J S (2009) The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading. BONE, 44 (5). pp. 930-935.

Saxon, L K and Lanyon, LE (2008) Assessment of the in vivo adaptive response to mechanical loading. Methods in Molecular Biology, 455 (vi). pp. 307-322.

Sugiyama, T and Saxon, L K and Zaman, G and Moustafa, A and Sunters, A and Price, J S and Lanyon, L E (2008) Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1-34) on trabecular and cortical bone in mice. BONE, 43 (2). pp. 238-248.

Bass, S L and Naughton, G and Saxon, L and Iuliano-Burns, S and Daly, R and Briganti, E M and Hume, C and Nowson, C (2007) Exercise and calcium combined results in a greater osteogenic effect than either factor alone: A blinded randomized placebo-controlled trial in boys. JOURNAL OF BONE AND MINERAL RESEARCH, 22 (3). pp. 458-464.

Armstrong, V J and Muzylak, M and Sunters, A and Zaman, G and Saxon, L K and Price, J S and Lanyon, L E (2007) Wnt/beta-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor alpha. JOURNAL OF BIOLOGICAL CHEMISTRY, 282. pp. 20715-27.

Book Section

De Souza, R L and Saxon, L K (2012) In Vivo Mechanical Loading. In: Bone Research Protocols. UNSPECIFIED, pp. 621-636.

Conference or Workshop Item

Windahl, S H and Saxon, L K and Borjesson, A E and Lagerquist, M K and Engdahl, C and Sjogren, K and Antal, M C and Krust, A and Chambon, P and Lanyon, L E and Price, J S and Ohlsson, C (2012) ESTROGEN RECEPTOR ALPHA AMPLIFIES THE OSTEOGENIC RESPONSE TO MECHANICAL LOADING IN A LIGAND-INDEPENDENT MANNER BY ITS ACTIVATION FUNCTION 1 BUT NOT 2. In: UNSPECIFIED.

Poulet, B and Saxon, L K and Barker, O and de Souza, R and Pitsillides, A A (2011) LOCALISED THICKENING OF SUBCHONDRAL BONE IN A MODEL OF LOADING-INDUCED ARTICULAR CARTILAGE LESIONS: PRODUCT OF CARTILAGE DAMAGE OR NOT? In: UNSPECIFIED.

Poulet, B and Saxon, L K and Barker, O and de Souza, R and Pitsillides, A A (2011) SUBCHONDRAL BONE THICKENING, WITH OR WITHOUT ARTICULAR CARTILAGE LESIONS, IN RESPONSE TO JOINT LOADING. In: UNSPECIFIED.

Moustafa, A M and Zaman, G and Saxon, L K and Lanyon, L E and Price, J S (2008) LOADING-RELATED REDUCTION IN OSTEOCYTE SCLEROSTIN EXPRESSION IN VIVO IS ASSOCIATED WITH BONE FORMATION IN TRABECULAR AND CORTICAL BONE. In: UNSPECIFIED.

Armstrong, V J and Muzylak, M and Sunters, A and Zaman, G and Saxon, L K and Price, J S and Lanyon, L E (2007) ESTROGEN RECEPTOR A IS REQUIRED FOR STRAIN-RELATED BETA-CATENIN SIGNALING IN OSTEOBLASTS. In: UNSPECIFIED.

Armstrong, V J and Muzylak, M and Sunters, A and Zaman, G and Saxon, L K and Price, J S and Lanyon, L E (2007) ESTROGEN RECEPTOR ALPHA IS REQUIRED FOR STRAIN-RELATED BETA-CATENIN SIGNALING IN OSTEOBLASTS. In: UNSPECIFIED.

Ducher, G and Black, J and Saxon, L and Daly, R and Turner, C and Bass, S (2007) EXERCISE INDUCED CHANGES IN THE MACRO-ARCHITECTURAL PARAMETERS OF CORTICAL BONE AS BOYS PROGRESS THROUGH PUBERTY: A LARGE WINDOW OF OPPORTUNITY? In: UNSPECIFIED.

Saxon, L K and Sugiyama, T and Price, J S and Lanyon, L E (2007) THE LRP5 GAIN OF FUNCTION MUTATION IS ASSOCIATED WITH AN INCREASED OSTEOGENIC RESPONSE TO LOADING IN TRABECULAR AS WELL AS CORTICAL BONE IN FEMALE BUT NOT MALE MICE. In: UNSPECIFIED.

Zaman, G and Saxon, L K and Muzylak, M and Price, J S and Lanyon, L E (2007) MECHANICAL LOADING INDUCED WNT/BETA-CATENIN SIGNALING IS COMPROMISED IN ER ALPHA-/- MOUSE TIBIA - IN VIVO MICROARRAY ANALYSIS. In: UNSPECIFIED.

Other

Sugiyama, T and Saxon, L K and Zaman, G and Moustafa, A and Sunters, A and Price, J S and Lanyon, L E (2009) ERRATUM TO MECHANICAL LOADING ENHANCES THE ANABOLIC EFFECTS OF INTERMITTENT PARATHYROID HORMONE (1-34) ON TRABECULAR AND CORTICAL BONE IN MICE. UNSPECIFIED.

This list was generated on Fri Feb 26 07:46:02 2021 GMT.