Browse by RVC Staff

Up a level
Export as [feed] Atom [feed] RSS
Group by: Item Type | No Grouping
Number of items: 69.

Article

Latham Birt, S H and Purcell, R and Botham, K M and Wheeler-Jones, C P D (2016) Endothelial HO-1 induction by model TG-rich lipoproteins is regulated through a NOX4-Nrf2 pathway. Journal of Lipid Research, 57 (7). pp. 1204-1218.

Botham, K M and Napolitano, M and Bravo, E (2015) The Emerging Role of Disturbed CoQ Metabolism in Nonalcoholic Fatty Liver Disease Development and Progression. Nutrients, 7 (12). pp. 9834-46.

Cabello-Moruno, R and Sinausia, L and Montero, E and Botham, K M and Avella, M A and Perona, J S (2015) Minor components of pomace olive oil enhance VLDL-receptor expression in macrophages when treated with postprandial triglyceride-rich lipoproteins. GRASAS Y ACEITES, 66 (4).

Purcell, R and Latham, S H and Botham, K M and Hall, W L and Wheeler-Jones, C P D (2014) High-fat meals rich in EPA plus DHA compared with DHA only have differential effects on postprandial lipemia and plasma 8-isoprostane F-2 alpha concentrations relative to a control high-oleic acid meal: a randomized controlled trial. American Journal of Clinical Nutrition, 100 (4). pp. 1019-1028.

Cabello-Moruno, R and Sinausia, L and Botham, K M and Montero, E and Avella, M and Perona, J S (2014) Postprandial phase time influences the uptake of TAG from postprandial TAG-rich lipoproteins by THP-1 macrophages. BRITISH JOURNAL OF NUTRITION, 112 (9). pp. 1469-1477.

Dawson, H J and Hibbert, A P and Chantler, P D and Botham, K M (2013) Myosin VI and associated proteins are expressed in human macrophages but do not play a role in foam cell formation in THP-1 cells. International Journal of Vascular Medicine, 2013. p. 516015.

Napolitano, M R and Botham, K M and Bravo, E (2013) Postprandial human triglyceride-rich lipoproteins increase chemoattractant protein secretion in human macrophages. CYTOKINE, 63 (1). pp. 18-26.

Botham, K M and Wheeler-Jones, C P D (2013) Postprandial lipoproteins and the molecular regulation of vascular homeostatis. Progress in Lipid Research, 52 (4). pp. 446-464.

Napolitano, M and Sennato, S and Botham, K M and Bordi, F and Bravo, E (2013) Role of macrophage activation in the lipid metabolism of postprandial triacylglycerol-rich lipoproteins. EXPERIMENTAL BIOLOGY AND MEDICINE, 238 (1). pp. 98-110.

Bravo, E and Palleschi, S and Rossi, B and Napolitano, M and Tiano, L and D'Amore, E and Botham, K M (2012) Coenzyme Q metabolism is disturbed in high fat diet-induced non alcoholic fatty liver disease in rats. International Journal of Molecular Sciences, 13 (2). pp. 1644-1657.

Castro Cabezas, M and Botham, K M and Mamo, J C and Proctor, S D (2012) Novel Aspects of Nonfasting Lipemia in relation to Vascular Biology. International Journal of Vascular Medicine, 212. 2 pages.

Graham, V S and Lawson, C and Wheeler-Jones, C P D and Perona, J S and Ruiz-Gutierrez, V and Botham, K M (2012) Triacylglycerol-rich lipoproteins derived from healthy donors fed different olive oils modulate cytokine secretion and cyclooxygenase-2 expression in macrophages: the potential role of oleanolic acid. European Journal of Nutrition, 51 (3). pp. 301-309.

Klop, B and Proctor, S and Mamo, J C L and Botham, K M and Castro Cabezas, M (2012) Understanding postprandial inflammation and its relationship to lifestyle behaviour and metabolic diseases. International Journal of Vascular Medicine. 11 pages.

Armengol Lopez, S and Botham, K M and Lawson, C (2012) The oxidative state of chylomicron remnants influences their modulation of human monocyte activation. International Journal of Vascular Medicine, 2012. 8 pages.

Bravo, E and Palleschi, S and Aspichueta, P and Buque, X and Rossi, B and Cano, A and Napolitano, M and Ochoa, B and Botham, K M (2011) High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway. Lipids in Health and Disease, 10 (60).

Bentley, C and Hathaway, N and Widdows, J and Bejta, F and De Pascale, C and Avella, M A and Wheeler-Jones, C P D and Botham, K M and Lawson, C (2011) Influence of chylomicron remnants on human monocyte activation in vitro. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 21 (11). pp. 871-878.

Graham, V S and Di Maggio, P and Armengol, S and Lawson, C and Wheeler-Jones, C P D and Botham, K M (2011) Inhibition of macrophage inflammatory cytokine secretion by chylomicron remnants is dependent on their uptake by the low density lipoprotein receptor. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1811 (3). pp. 209-220.

Garonna, E and Botham, K M and Birdsey, G M and Randi, A M and Gonzalez-Perez, R R and Wheeler-Jones, C P D (2011) Vascular Endothelial Growth Factor Receptor-2 Couples Cyclo-Oxygenase-2 with Pro-Angiogenic Actions of Leptin on Human Endothelial Cells. PLoS One, 6 (4). e18823.

Dalla-Riva, J and Garonna, E and Elliott, J and Botham, K M and Wheeler-Jones, C P D (2010) Endothelial cells as targets for chylomicron remnants. Atherosclerosis Supplements, 11 (1). pp. 31-37.

Bravo, E and Napolitan, M and Botham, K M (2010) Postprandial lipid metabolism: the missing link between lifestyle habits and the increasing incidence of metabolic diseases in Western Countries? Open Translational Medicine Journal, 2. pp. 1-13.

De Pascale, C and Graham, V S and Fowkes, R C and Wheeler-Jones, C P D and Botham, K M (2010) SUPPRESSION OF NUCLEAR FACTOR-kappaB ACTIVITY IN MACROPHAGES BY CHYLOMICRON REMNANTS: MODULATION BY THE FATTY ACID COMPOSITION OF THE PARTICLES. Atherosclerosis Supplements, 11 (2). P234.

Lopez-Soldado, I and Avella, M A and Botham, K M (2009) Differential influence of different dietary fatty acids on very low-density lipoprotein secretion when delivered to hepatocytes in chylomicron remnants. Metabolism-Clinical and Experimental, 58 (2). pp. 186-195.

Cano, A and Ciaffoni, F and Safwat, G M and Aspichueta, P and Ochoa, B and Bravo, E and Botham, K M (2009) Hepatic VLDL assembly is disturbed in a rat model of nonalcoholic fatty liver disease: is there a role for dietary coenzyme Q? Journal of Applied Physiology, 107 (3). pp. 707-717.

Safwat, G M and Pisano, S and D'Amore, E and Borioni, G and Napolitano, M and Kamal, A A and Ballanti, P and Botham, K M and Bravo, E (2009) Induction of non-alcoholic fatty liver disease and insulin resistance by feeding a high-fat diet in rats: does coenzyme Q monomethyl ether have a modulatory effect? Nutrition, 25 (11-12). pp. 1157-1168.

Lopez-Soldado, I and Avella, M A and Botham, K M (2009) Suppression of VLDL secretion by cultured hepatocytes incubated with chylomicron remnants enriched in n-3 polyunsaturated fatty acids is regulated by hepatic nuclear factor-4 alpha. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1791 (12). pp. 1181-1189.

De Pascale, C and Graham, V and Fowkes, R C and Wheeler-Jones, C P D and Botham, K M (2009) Suppression of nuclear factor-kappaB activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of the particles. FEBS JOURNAL, 276 (19). pp. 5689-5702.

Perona, J S and Avella, M A and Botham, K M and Ruiz-Gutierrez, V (2008) Differential modulation of hepatic very low-density lipoprotein secretion by triacylglycerol-rich lipoproteins derived from different oleic-acid rich dietary oils. BRITISH JOURNAL OF NUTRITION, 99 (1). pp. 29-36.

Napolitano, M and De Pascale, C and Wheeler-Jones, C P D and Botham, K M and Bravo, E (2007) Effects of lycopene on the induction of foam cell formation by modified LDL. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 293 (6). E1820-E1827.

Bejta, F and Napolitano, M and Botham, K M and Bravo, E (2007) Incorporation of lycopene into chylomicron remnant-like particles inhibits their uptake by HepG2 cells. LIFE SCIENCES, 80 (18). pp. 1699-1705.

Bejta, F and Moore, E H and Avella, M A and Gough, P J and Suckling, K E and Botham, K M (2007) Oxidation of chylomicron remnant-like particles inhibits their uptake by THP-1 macrophages by apolipoprotein E-dependent processes. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1771 (7). pp. 901-910.

De Pascale, C and Avella, M A and Perona, J S and Ruiz-Gutierrez, V and Wheeler-Jones, C P D and Botham, K M (2006) Fatty acid composition of chylomicron remnant-like particles influences their uptake and induction of lipid accumulation in macrophages. FEBS JOURNAL, 273 (24). pp. 5632-5640.

Bravo, E and Napolitano, M and Lopez-Soldado, I and Valeri, M and Botham, K M and Stefanutti, C (2006) Hypercholesterolaemia alters the responses of the plasma lipid profile and inflammatory markers to supplementation of the diet with n-3 polyunsaturated fatty acids from fish oil. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 36 (11). pp. 788-795.

Perona, J S and Avella, M A and Botham, K M and Ruiz-Gutierrez, V (2006) Uptake of triacylglycerol-rich lipoproteins of differing triacylglycerol molecular species and unsaponifiable content by liver cells. BRITISH JOURNAL OF NUTRITION, 95 (5). pp. 889-897.

Botham, K M and Bravo, E and Elliott, J and Wheeler-Jones, C P D (2005) Direct interaction of dietary lipids carried in chylomicron remnants with cells of the artery wall: Implications for atherosclerosis development. CURRENT PHARMACEUTICAL DESIGN, 11 (28). pp. 3681-3695.

Moore, E H and Bejta, F and Avella, M A and Suckling, K E and Botham, K M (2005) Efflux of lipid from macrophages after induction of lipid accumulation by chylomicron remnants. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1735 (1). pp. 20-29.

Napolitano, M and Avella, M and Goode, N T and Botham, K M and Bravo, E (2004) Cholesterol esterification in human monocyte-derived macrophages is inhibited by protein kinase C with dual roles for mitogen activated protein kinases. CELL BIOLOGY INTERNATIONAL, 28 (10). pp. 717-725.

Batt, K V and Patel, L and Botham, K M and Suckling, K E (2004) Chylomicron remnants and oxidised low density lipoprotein have differential effects on the expression of mRNA for genes involved in human macrophage foam cell formation. JOURNAL OF MOLECULAR MEDICINE-JMM, 82 (7). pp. 449-458.

Batt, K V and Avella, M A and Moore, E H and Jackson, B F and Suckling, K E and Botham, K M (2004) Differential effects of low-density lipoprotein and chylomicron remnants on lipid accumulation in human macrophages. EXPERIMENTAL BIOLOGY AND MEDICINE, 229 (6). pp. 528-537.

Moore, E H and Napolitano, M and Avella, M A and Bejta, F and Suckling, K E and Bravo, E and Botham, K M (2004) Protection of chylomicron remnants from oxidation by incorporation of probucol into the particles enhances their uptake by human macrophages and increases lipid accumulation in the cells. EUROPEAN JOURNAL OF BIOCHEMISTRY, 271 (12). pp. 2417-2427.

Napolitano, M and Bravo, E and Avella, M A and Chico, Y and Ochoa, B and Botham, K M and Rivabene, R (2004) The fatty acid composition of chylomicron remnants influences their propensity to oxidate. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 14 (5). pp. 241-247.

Napolitano, M and Avella, M and Botham, K M and Bravo, E (2003) Chylomicron remnant induction of lipid accumulation in J774 macrophages is associated with up-regulation of triacylglycerol synthesis which is not dependent on oxidation of the particles. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1631 (3). pp. 255-264.

Goulter, A B and Avella, M A and Botham, K M and Elliott, J (2003) Chylomicron-remnant-like particles inhibit the basal nitric oxide pathway in porcine coronary artery and aortic endothelial cells. CLINICAL SCIENCE, 105 (3). pp. 363-371.

Moore, E H and Napolitano, M and Prosperi, A and Avella, M A and Suckling, K E and Bravo, E and Botham, K M (2003) Incorporation of lycopene into chylomicron remnant-like particles enhances their induction of lipid accumulation in macrophages. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 312 (4). pp. 1216-1219.

Maldonado, E N and Chico, Y and Botham, K M and Aveldano, M I and Ochoa, B (2003) Influence of the fatty acid composition of lipids in chylomicron remnants derived from fish or corn oil on the lipid profile of cultured rat hepatocytes. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 59.

Botham, K M and Zheng, X Z and Napolitano, M and Avella, M A and Cavallari, C and Rivabene, R and Bravo, E (2003) The effects of dietary n-3 polyunsaturated fatty acids delivered in chylomicron remnants on the transcription of genes regulating synthesis and secretion of very-low-density lipoprotein by the liver: Modulation by cellular oxidative state. EXPERIMENTAL BIOLOGY AND MEDICINE, 228 (2). pp. 143-151.

Goulter, A B and Avella, M A and Elliott, J and Botham, K M (2002) Chylomicron-remnant-like particles inhibit receptor-mediated endothelium-dependent vasorelaxation in pig coronary arteries. CLINICAL SCIENCE, 103 (5). pp. 451-460.

Napolitano, M and Calcabrini, A and Botham, K M and Bravo, E (2002) Role of estrogen in the regulation of cholesteryl ester synthesis in macrophages: the interaction between native and modified low density lipoprotein and human monocyte-derived-macrophages. CLINICAL BIOCHEMISTRY, 35 (8). pp. 597-605.

Zheng, X Z and Rivabene, R and Cavallari, C and Napolitano, M and Avella, M A and Bravo, E and Botham, K M (2002) The effects of chylomicron remnants enriched in n-3 or n-6 polyunsaturated fatty acids on the transcription of genes regulating their uptake and metabolism by the liver: Influence of cellular oxidative state. FREE RADICAL BIOLOGY AND MEDICINE, 32 (11). pp. 1123-1131.

Zheng, X Z and Avella, M A and Botham, K M (2001) Comparison of the effects of dietary n-3 and n-6 polyunsaturated fatty acids on very-low-density lipoprotein secretion when delivered to hepatocytes in chylomicron remnants. BIOCHEMICAL JOURNAL, 357. pp. 481-487.

Napolitano, M and Batt, K V and Avella, M A and Bravo, E and Botham, K M (2001) Lipid synthesis in macrophages derived from the human cell line THP-1: modulation of the effects of native and oxidized chylomicron-remnant-like particles by oestrogen. CLINICAL SCIENCE, 101 (4). pp. 403-413.

Bravo, E and Cantafora, A and Avella, M A and Botham, K M (2001) Metabolism of chylomicron cholesterol is delayed by estrogen. An in vivo study in the rat. EXPERIMENTAL BIOLOGY AND MEDICINE, 226 (2). pp. 112-118.

Napolitano, M and Rivabene, R and Avella, M A and Amicone, L and Tripodi, M and Botham, K M and Bravo, E (2001) Oxidation affects the regulation of hepatic lipid synthesis by chylomicron remnants. FREE RADICAL BIOLOGY AND MEDICINE, 30 (5). pp. 506-515.

Lambert, M S and Avella, M A and Berhane, Y and Shervill, E and Botham, K M (2001) The differential hepatic uptake of chylomicron remnants of different fatty acid composition is not mediated by hepatic lipase. BRITISH JOURNAL OF NUTRITION, 85. pp. 575-582.

Lambert, M S and Avella, M A and Berhane, Y and Shervill, E and Botham, K M (2001) The fatty acid composition of chylomicron remnants influences their binding and internalization by isolated hepatocytes. EUROPEAN JOURNAL OF BIOCHEMISTRY, 268 (14). pp. 3983-3992.

Botham, K M and Maldonado, E N and Chico, Y and Zheng, X Z and Avella, M A and Ochoa, B (2001) The influence of chylomicron remnants on cholesteryl ester metabolism in cultured rat hepatocytes: comparison of the effects of particles enriched in n-3 or n-6 polyunsaturated fatty acids. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1534 (2-3). pp. 96-109.

Napolitano, M and Rivabene, R and Avella, M A and Botham, K M and Bravo, E (2001) The internal redox balance of the cells influences the metabolism of lipids of dietary origin by J774 macrophages: Implications for foam cell formation. JOURNAL OF VASCULAR RESEARCH, 38 (4). pp. 350-360.

Conference or Workshop Item

Sinausia, L and Cabello-Moruno, R and Botham, K M and Montero, E and Perona, J S (2014) TRIGLICERIDE-RICH LIPOPROTEINS ARE TAKEN UP BY MACROPHAGES DIFFERENTLY VIA RECEPTOR-MEDIATED PATHWAYS DURING THE POSTPRANDIAL PERIOD. In: UNSPECIFIED.

Botham, K M and Pollard, A S and Jacks, K and Thomas, C and Avella, M A and Lawson, C (2013) EFFECT OF CHEMICAL OR OXIDATIVE MODIFICATION OF CHYLOMICRON REMNANTS ON MICROPARTICLE PRODUCTION FROM HUMAN MONOCYTES. In: UNSPECIFIED.

Purcell, R and Latham, S H and Botham, K M and Hall, W and Wheeler-Jones, C P D (2013) HIGH FAT MEALS CONTAINING N-3 PUFAS GENERATE TRIGLYCERIDE-RICH LIPOPROTEINS WITH PROTECTIVE ACTIONS ON AORTIC ENDOTHELIAL CELLS. In: UNSPECIFIED.

Latham, S H and Purcell, R and Botham, K M and Wheeler-Jones, C P D (2013) MECHANISMS OF ENDOTHELIAL PROTECTION MEDIATED BY N-3 PUFAS CARRIED IN CHYLOMICRON REMNANTS. In: UNSPECIFIED.

Botham, K M and Graham, V S and Lawson, C and Wheeler-Jones, C P D (2010) DOWN-REGULATION OF MACROPHAGE CYTOKINE SECRETION BY CHYLOMICRON REMNANTS: ROLE OF THE LDL RECEPTOR. In: UNSPECIFIED.

Botham, K M and Napolitano, M and Bravo, E (2010) INDUCTION OF MACROPHAGE MONOCYTE CHEMOATTRACTANT SECRETION BY TRIACYLGLYCEROL RICH LIPOPROTEINs. In: UNSPECIFIED.

Dalla-Riva, J and Garonna, E and Elliott, J and Botham, K M and Wheeler-Jones, C P D (2010) INFLUENCE OF LIPID CONTENT AND OXIDATION STATE OF CHYLOMICRON REMNANTS ON ENDOTHELIAL CELL SIGNALLING AND FUNCTION. In: UNSPECIFIED.

Botham, K M (2008) Oxidation of chylomicron remnants and vascular dysfunction. In: UNSPECIFIED.

Lopez-Soldado, I and Avella, M A and Botham, K M (2007) Comparison of the effects of dietary saturated/mono-unsaturated and polyunsaturated fatty acids on very-low-density lipoprotein secretion when delivered to hepatocytes in chylomicron remnant-like particles. In: UNSPECIFIED.

Bentley, C and Bejta, F and De Pascale, C and Avella, M A and Wheeler-Jones, C P D and Botham, K M and Lawson, C (2007) Dietary fats induce human monocyte activation in vitro. In: UNSPECIFIED.

Botham, K M and Wheeler-Jones, C P D (2007) Introduction to the Biochemical Society Focused Meeting on Diet and Cardiovascular Health: Chylomicron Remnants and Their Emerging Roles in Vascular Dysfunction in Atherosclerosis. In: UNSPECIFIED.

Botham, K M and Moore, E H and De Pascale, C and Bejta, F (2007) The induction of macrophage foam cell formation by chylomicron remnants. In: UNSPECIFIED.

Evans, M and Berhane, Y and Botham, K M and Elliott, J and Wheeler-Jones, C P D (2004) Chylomicron-remnant-like particles modify production of vasoactive mediators by endothelial cells. In: UNSPECIFIED.

This list was generated on Sat Sep 25 07:48:10 2021 BST.