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Puig, B and Altmeppen, H C and Linsenmeier, L and Chakroun, K and Wegwitz, F and Piontek, U K and Tatzelt, J and Bate, C and Magnus, T and Glatzel, M (2019) GPI-anchor signal sequence influences PrPC sorting, shedding and signalling, and impacts on different pathomechanistic aspects of prion disease in mice. PLoS Pathogens, 15 (1). e1007520.

Osborne, C and West, E and Bate, C (2018) The phospholipase A2 pathway controls a synaptic cholesterol ester cycle and synapse damage. Journal of Cell Science, 131 (8).

Bate, C and Williams, A (2018) Monomeric amyloid-ß reduced amyloid-ß oligomer-induced synapse damage in neuronal cultures. NEUROBIOLOGY OF DISEASE, 111. pp. 48-58.

McHale-Owen, H and Bate, C (2018) Cholesterol ester hydrolase inhibitors reduce the production of synaptotoxic amyloid-beta oligomers. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1864 (3). pp. 649-659.

Williams, R S B and Bate, C (2018) Valproic acid and its congener propylisopropylacetic acid reduced the amount of soluble amyloid-ß oligomers released from 7PA2 cells. NEUROPHARMACOLOGY, 128. pp. 54-62.

Bate, C (2017) Breaking the Cycle, Cholesterol Cycling, and Synapse Damage in Response to Amyloid-ß. Journal of Experimental Neuroscience, 11.

Bate, C (2017) Can we switch production of toxic Aß oligomers to neuroprotective Aß monomers to allow synapse regeneration? NEURAL REGENERATION RESEARCH, 12 (9). pp. 1437-1438.

West, E and Osborne, C and Bate, C (2017) The cholesterol ester cycle regulates signalling complexes and synapse damage caused by amyloid-ß. Journal of Cell Science, 130. pp. 3050-3059.

Nolan, W and McHale-Owen, H and Bate, C (2017) Sialylated glycosylphosphatidylinositols suppress the production of toxic amyloid-ß oligomers. BIOCHEMICAL JOURNAL, 474 (17). pp. 3045-3058.

Bate, C and Nolan, W and McHale-Owen, H and Williams, A (2016) Sialic Acid within the Glycosylphosphatidylinositol Anchor Targets the Cellular Prion Protein to Synapses. JOURNAL OF BIOLOGICAL CHEMISTRY, 291 (33). pp. 17093-101.

Bate, C and Nolan, W and Williams, A (2016) Does the tail wag the dog? How the structure of a glycosylphosphatidylinositol anchor affects prion formation. Prion, 10 (2). pp. 127-30.

Osborne, C and West, E and Nolan, W and McHale-Owen, H and Williams, A and Bate, C (2016) Glimepiride protects neurons against amyloid-beta-induced synapse damage. NEUROPHARMACOLOGY, 101. pp. 225-236.

Williams, R S B and Bate, C (2016) An in vitro model for synaptic loss in neurodegenerative diseases suggests a neuroprotective role for valproic acid via inhibition of cPLA(2) dependent signalling. NEUROPHARMACOLOGY, 101. pp. 566-575.

Bate, C and Nolan, W and Williams, A (2016) Glycosylphosphatidylinositols: More than just an anchor? Communicative & Integrative Biology, 9 (2). e1149671-e1149671.

Bate, C and Nolan, W and McHale-Owen, H and Williams, A (2016) Sialic Acid on the Glycosylphosphatidylinositol Anchor Regulates PrP-mediated Cell Signaling and Prion Formation. JOURNAL OF BIOLOGICAL CHEMISTRY, 291 (33). pp. 17093-17101.

West, E and Osborne, C and Nolan, W and Bate, C (2015) Monoacylated Cellular Prion Proteins Reduce Amyloid-beta-Induced Activation of Cytoplasmic Phospholipase A2 and Synapse Damage. Biology, 4 (2). pp. 367-82.

Bate, C and Williams, A (2015) a-Synuclein-Induced Synapse Damage in Cultured Neurons Is Mediated by Cholesterol-Sensitive Activation of Cytoplasmic Phospholipase A2. Biomolecules, 5 (1). pp. 178-93.

Bate, C (2015) Enhanced neuronal degradation of amyloid-beta oligomers allows synapse regeneration. NEURAL REGENERATION RESEARCH, 10 (5). pp. 700-701.

Bate, C and Williams, A (2015) cAMP-Inhibits Cytoplasmic Phospholipase A(2) and Protects Neurons against Amyloid-beta-Induced Synapse Damage. Biology, 4 (3). pp. 591-606.

Ingham, V and Williams, A and Bate, C (2014) Glimepiride reduces CD14 expression and cytokine secretion from macrophages. JOURNAL OF NEUROINFLAMMATION, 11.

Simmons, C and Ingham, V and Williams, A and Bate, C (2014) Platelet-activating factor antagonists enhance intracellular degradation of amyloid-beta(42) in neurons via regulation of cholesterol ester hydrolases. ALZHEIMERS RESEARCH & THERAPY, 6 (2).

Bate, C and Williams, A (2012) Clustering of sialylated glycosylphosphatidylinositol anchors mediates PrP-induced activation of cytoplasmic phospholipase A(2) and synapse damage. Prion, 6 (4). pp. 350-353.

Amijee, H and Bate, C and Williams, A and Virdee, J and Jeggo, R and Spanswick, D and Scopes, D I C and Treherne, J M and Mazzitelli, S and Chawner, R and Eyers, C E and Doig, A J (2012) The N-Methylated Peptide SEN304 Powerfully Inhibits A beta(1-42) Toxicity by Perturbing Oligomer Formation. Biochemistry, 51 (42). pp. 8338-8352.

Bate, C and Williams, A (2012) Neurodegeneration Induced by Clustering of Sialylated Glycosylphosphatidylinositols of Prion Proteins. JOURNAL OF BIOLOGICAL CHEMISTRY, 287 (11). pp. 7935-7944.

Bate, C and Williams, A (2011) Amyloid-beta-induced Synapse Damage Is Mediated via Cross-linkage of Cellular Prion Proteins. JOURNAL OF BIOLOGICAL CHEMISTRY, 286 (44). pp. 37955-37963.

Bate, C and Williams, A (2011) Ethanol protects cultured neurons against amyloid-beta and alpha-synuclein-induced synapse damage. NEUROPHARMACOLOGY, 61 (8). pp. 1406-1412.

Bate, C and Ingham, V and Williams, A (2011) Inhibition of phospholipase A(2) increased the removal of the prion derived peptide PrP82-146 from cultured neurons. NEUROPHARMACOLOGY, 60 (2-3). pp. 365-372.

Bate, C and Williams, A (2011) Monoacylated Cellular Prion Protein Modifies Cell Membranes, Inhibits Cell Signaling, and Reduces Prion Formation. JOURNAL OF BIOLOGICAL CHEMISTRY, 286 (11). pp. 8752-8758.

Bate, C and Williams, A (2011) The cellular prion protein with a monoacylated glycosylphosphatidylinositol anchor modifies cell membranes, inhibits cell signaling and reduces prion formation. Prion, 5 (2). pp. 65-68.

Bate, C and Gentleman, S and Williams, A (2010) Alpha-synuclein induced synapse damage is enhanced by amyloid-beta. Molecular Neurodegeneration, 5 (55).

Bate, C and Williams, A (2010) Amyloid-beta(1-40) Inhibits Amyloid-beta(1-42) Induced Activation of Cytoplasmic Phospholipase A(2) and Synapse Degeneration. Journal of Alzheimer's Disease, 21 (3). pp. 985-993.

Jones, D R and Taylor, W A and Bate, C and David, M and Tayebi, M (2010) A Camelid Anti-PrP Antibody Abrogates PrPSc Replication in Prion-Permissive Neuroblastoma Cell Lines. PLoS One, 5 (3).

Tayebi, M and David, M and Bate, C and Jones, D R and Taylor, W and Morton, R and Pollard, J and Hawke, S (2010) Epitope-specific anti-prion antibodies upregulate apolipoprotein E and disrupt membrane cholesterol homeostasis. JOURNAL OF GENERAL VIROLOGY, 91 (Pt12). pp. 3105-3115.

Bate, C and Tayebi, M and Williams, A (2010) Glycosylphosphatidylinositol Anchor Analogues Sequester Cholesterol and Reduce Prion Formation. JOURNAL OF BIOLOGICAL CHEMISTRY, 285 (29). pp. 22017-22026.

Bate, C and Tayebi, M and Williams, A (2010) Phospholipase A(2) inhibitors protect against prion and A beta mediated synapse degeneration. Molecular Neurodegeneration, 5 (13).

Bate, C and Tayebi, M and Salmona, M and Diomede, L and Williams, A (2010) Polyunsaturated Fatty Acids Protect Against Prion-Mediated Synapse Damage In Vitro. Neurotoxicity Research, 17 (3). pp. 203-214.

Tayebi, M and Taylor, W A and Jones, D R and Bate, C and David, M (2010) PrP-specific camel antibodies with the ability to immunodetect intracellular prion protein. JOURNAL OF GENERAL VIROLOGY, 91. pp. 2121-2131.

Bate, C and Tayebi, M and Williams, A (2010) A glycosylphosphatidylinositol analogue reduced prion-derived peptide mediated activation of cytoplasmic phospholipase A(2), synapse degeneration and neuronal death. NEUROPHARMACOLOGY, 59 (1-2). pp. 93-99.

Bate, C and Tayebi, M and Williams, A (2010) The glycosylphosphatidylinositol anchor is a major determinant of prion binding and replication. BIOCHEMICAL JOURNAL, 428. pp. 95-101.

Bate, C and Tayebi, M and Diomede, L and Salmona, M and Williams, A (2009) Glimepiride Reduces the Expression of PrPC, Prevents PrPSc Formation and Protects against Prion Mediated Neurotoxicity. PLoS One, 4 (12). e8221.

Bate, C and Tayebi, M and Williams, A (2008) Cholesterol esterification reduces the neurotoxicity of prions. NEUROPHARMACOLOGY, 54 (8). pp. 1247-1253.

Bate, C and Williams, A (2008) Do prion-induced changes in cholesterol trigger neurodegeneration? Future Neurology, 3 (4). pp. 367-370.

Bate, C and Marshall, V and Colombo, L and Diomede, L and Salmona, M and Williams, A (2008) Docosahexaenoic and eicosapentaenoic acids increase neuronal death in response to HuPrP82-146 and A beta 1-42. NEUROPHARMACOLOGY, 54 (6). pp. 934-943.

Bate, C and Tayebi, M and Diomede, L and Salmona, M and Williams, A (2008) Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells. Bmc Biology, 6.

Bate, C and Tayebi, M and Williams, A (2008) Ginkgolides protect against amyloid-beta(1-42)-mediated synapse damage in vitro. Molecular Neurodegeneration, 3 (1).

Bate, C and Tayebi, M and Williams, A (2008) Sequestration of free cholesterol in cell membranes by prions correlates with cytoplasmic phospholipase A(2) activation. Bmc Biology, 6.

Bate, C and Rumbold, L and Williams, A (2007) Cholesterol synthesis inhibitors protect against platelet-activating factor-induced neuronal damage. JOURNAL OF NEUROINFLAMMATION, 4. p. 5.

Kempster, S and Bate, C and Williams, A (2007) Simvastatin treatment prolongs the survival of scrapie-infected mice. NEUROREPORT, 18 (5). pp. 479-482.

Wilson, R and Bate, C and Boshuizen, R and Williams, A and Brewer, J (2007) Squalestatin alters the intracellular trafficking of a neurotoxic prion peptide. Bmc Neuroscience, 8.

Bate, C and Williams, A (2007) Squalestatin protects neurons and reduces the activation of cytoplasmic phospholipase A(2) by A beta(1-42). NEUROPHARMACOLOGY, 53 (2). pp. 222-231.

Bate, C and Rumbold, L and Williams, A (2007) Statins reduce the neurotoxicity of platelet-activating factor. JOURNAL OF NEUROINFLAMMATION, 4 (5).

Tayebi, M and Bate, C and Hawke, S and Williams, A (2007) A role for B lymphocytes in anti-infective prion therapies? EXPERT REVIEW OF ANTI-INFECTIVE THERAPY, 5 (4). pp. 631-638.

Bate, C and Kempster, S and Last, V and Williams, A (2006) Interferon-gamma increases neuronal death in response to amyloid-beta(1-42). JOURNAL OF NEUROINFLAMMATION, 3. p. 7.

Bate, C and Kempster, S and Williams, A (2006) Platelet-activating factor antagonists protect amyloid-beta damaged neurons from microglia-mediated death. NEUROPHARMACOLOGY, 51 (2). pp. 173-181.

Bate, C and Kempster, S and Williams, A (2006) Prostaglandin D-2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells. NEUROPHARMACOLOGY, 50 (2). pp. 229-237.

Bate, C and Boshuizen, R and Williams, A (2005) Microglial cells kill prion-damaged neurons in vitro by a CD14-dependent process. JOURNAL OF NEUROIMMUNOLOGY, 170 (1-2). pp. 62-70.

Bate, C and Williams, A (2004) Detoxified lipopolysaccharide reduces microglial cell killing of prion-infected neurons. NEUROREPORT, 15 (18). pp. 2765-2768.

Bate, C and Langeveld, J and Williams, A (2004) Manipulation of PrPres production in scrapie-infected neuroblastoma cells. JOURNAL OF NEUROSCIENCE METHODS, 138 (1-2). pp. 217-223.

Bate, C and Veerhuis, R and Eikelenboom, P and Williams, A E (2004) Microglia kill amyloid-beta(1-42) damaged neurons by a CD14-dependent process. NEUROREPORT, 15 (9). pp. 1427-1430.

Bate, C and Reid, S W J and Williams, A (2004) Phospholipase A(2) inhibitors or platelet-activating factor antagonists prevent prion replication. JOURNAL OF BIOLOGICAL CHEMISTRY, 279 (35). pp. 36405-36411.

Bate, C and Williams, A (2004) Role of glycosylphosphatidylinositols in the activation of phospholipase A(2) and the neurotoxicity of prions. JOURNAL OF GENERAL VIROLOGY, 85 (85). pp. 3797-3804.

Bate, C and Salmona, M and Diomede, L and Williams, A (2004) Squalestatin cures prion-infected neurons and protects against prion neurotoxicity. JOURNAL OF BIOLOGICAL CHEMISTRY, 279 (15). pp. 14983-14990.

Bate, C and Salmona, M and Williams, A (2004) The role of platelet activating factor in prion and amyloid-beta neurotoxicity. NEUROREPORT, 15 (3). pp. 509-513.

Conference or Workshop Item

Williams, A and Bate, C (2009) LIPID RAFTS, CELL SIGNALLING, PRION FORMATION AND NEURODEGENERATION IN PRION DISEASES. In: UNSPECIFIED.

This list was generated on Sat Sep 25 07:46:36 2021 BST.