Items where Author is "Werling, D"

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Holder, A and Garty, R and Elder, C and Mesnard, P and Laquerbe, C and Bartens, M-C and Salavati, M and Shabbir, M and Tzelos, T and Connelly, T and Villarreal-Ramos, B and Werling, D (2020) Analysis of Genetic Variation in the Bovine SLC11A1 Gene, Its Influence on the Expression of NRAMP1 and Potential Association With Resistance to Bovine Tuberculosis. Frontiers in Microbiology, 11. ISSN 1664-302X

Vats, A and Gautam, D and Maharana, J and Chera, J S and Kumar, S and Werling, D and De, S (2020) Poly I:C stimulation in-vitro as a marker for an antiviral response in different cell types generated from Buffalo (Bubalus bubalis). Molecular Immunology, 121. pp. 136-143.

Vats, A and Gautam, D and Maharana, J and Singh Chera, J and Kumar, S and Rout, P K and Werling, D and De, S (2020) Poly I:C stimulation in-vitro as a marker for an antiviral response in different cell types generated from Buffalo (Bubalus bubalis). Molecular Immunology, 121. pp. 136-143. ISSN 01615890

Soutter, F and Werling, D and Tomley, F M and Blake, D P (2020) Poultry Coccidiosis: Design and Interpretation of Vaccine Studies. Frontiers in Veterinary Science, 7. ISSN 2297-1769

Jégouzo, S A F and Nelson, C and Hardwick, T and Wong, S T A and Lau, N K K and Neoh, G K E and Castellanos-Rueda, R and Huang, Z and Mignot, B and Hirdaramani, A and Howitt, A and Frewin, K and Shen, Z and Fox, R J and Wong, R and Ando, M and Emony, L and Zhu, H and Holder, A L and Werling, D and Krishnan, N and Robertson, B D and Clements, A and Taylor, M E and Drickamer, K (2020) Mammalian lectin arrays for screening host-microbe interactions. JOURNAL OF BIOLOGICAL CHEMISTRY, 295 (14). pp. 4541-4555.

Jégouzo, S A F and Feinberg, H and Morrison, A and Holder, A and May, A and Huang, Z and Jiang, L and Lasanajak, Y and Smith, D F and Werling, D and Drickamer, K and Weis, W I and Taylor, M E (2019) CD23 is a glycan-binding receptor in some mammalian species. JOURNAL OF BIOLOGICAL CHEMISTRY.

Pilla, R and Guard, B C and Steiner, J M and Gaschen, F P and Olson, E and Werling, D and Allenspach, K and Schmitz, S S and Suchodolski, J S (2019) Administration of a Synbiotic Containing Enterococcus faecium Does Not Significantly Alter Fecal Microbiota Richness or Diversity in Dogs With and Without Food-Responsive Chronic Enteropathy. Frontiers in Veterinary Science.

Tombacz, K and Peters, L M and Chang, Y M and Steele, M and Werling, D and Gibson, A J (2019) Pegbovigrastim treatment in vivo does not affect granulocyte ability to migrate to endometrial cells and kill bacteria in vitro in healthy cows. JOURNAL OF DAIRY SCIENCE, 102 (10). pp. 9389-9395.

García-Sánchez, M and Jiménez-Pelayo, L and Horcajo, P and Regidor-Cerrillo, J and Ólafsson, E B and Bhandage, A K and Barragan, A and Werling, D and Ortega-Mora, L M and Collantes-Fernández, E (2019) Differential Responses of Bovine Monocyte-Derived Macrophages to Infection by Neospora caninum Isolates of High and Low Virulence. Frontiers in Immunology, 10 (915).

Grelet, C and Vanlierde, A and Hostens, M and Foldager, L and Salavati, M and Ingvartsen, K L and Crowe, M and Sorensen, M T and Froidmont, E and Ferris, C P and Marchitelli, C and Becker, F and Larsen, T and Carter, F and Dehareng, F and McLoughlin, N and Fahey, A and Matthews, E and Santoro, A and Byrne, C and Rudd, P and O'Flaherty, R and Hallinan, S and Wathes, D C and Cheng, Z R and Fouladi-Nashta, A A and Pollott, G E and Werling, D and Bernardo, B S and Wylie, A and Bell, M and Vaneetvelde, M and Hermans, K and Opsomer, G and Moerman, S and Dekoster, J and Bogaert, H and Vandepitte, J and Vandevelde, L and Vanranst, B and Hoglund, J and Dahl, S and Ostergaard, S and Rothmann, J and Krogh, M and Meyer, E and Gaillard, C and Ettema, J and Rousing, T and Signorelli, F and Napolitano, F and Moioli, B and Crisa, A and Buttazzoni, L and McClure, J and Matthews, D and Kearney, F and Cromie, A and McClure, M and Zhang, S J and Chen, X and Chen, H C and Zhao, J L and Yang, L G and Hua, G H and Tan, C and Wang, G Q and Bonneau, M and Pompozzi, A and Pearn, A and Evertson, A and Kosten, L and Fogh, A and Andersen, T and Lucey, M and Elsik, C and Conant, G and Taylor, J and Gengler, N and Georges, M and Colinet, F and Pamplona, M R and Hammami, H and Bastin, C and Takeda, H and Laine, A and Van Laere, A S and Schulze, M and Vera, S P and GplusE Consortium (2019) Potential of milk mid-IR spectra to predict metabolic status of cows through blood components and an innovative clustering approach. Animal, 13 (3). pp. 649-658.

De Koster, J and Salavati, M and Grelet, C and Crowe, M A and Matthews, E and O'Flaherty, R and Opsomer, G and Foldager, L and Hostens, M and McLoughlin, N and Fahey, A and Santoro, A and Byrne, C and Rudd, P and Hallinan, S and Wathes, D C and Cheng, Z R and Fouladi-Nashta, A A and Pollott, G and Werling, D and Bernardo, B S and Wylie, A and Bell, M and Vaneetvelde, M and Hermans, K and Moerman, S and Bogaert, H and Vandepitte, J and Vandevelde, L and Vanranst, B and Hoglund, J and Dahl, S and Ostergaard, S and Rothmann, J and Krogh, M and Meyer, E and Gaillard, C and Ettema, J and Rousing, T and Signorelli, F and Napolitano, F and Moioli, B and Crisa, A and Buttazzoni, L and McClure, J and Matthews, D and Kearney, F and Cromie, A and McClure, M and Zhang, S J and Chen, X and Chen, H C and Zhao, J L and Yang, L G and Hua, G H and Tan, C and Wang, G Q and Bonneau, M and Pompozzi, A and Pearn, A and Evertson, A and Kosten, L and Fogh, A and Andersen, T and Lucy, M and Elsik, C and Conant, G and Taylor, J and Gengler, N and Georges, M and Colinet, F and Pamplona, M R and Hammami, H and Bastin, C and Takeda, H and Laine, A and Van Laere, A S and Schulze, M and Vrea, S P (2019) Prediction of metabolic clusters in early-lactation dairy cows using models based on milk biomarkers. JOURNAL OF DAIRY SCIENCE, 102 (3). pp. 2631-2644.

Tombacz, K and Burgess, G and Holder, A L and Werners, A and Werling, D (2018) Toxoplasma gondii profilin does not stimulate an innate immune response through bovine or human TLR5. Innate Immunity. (In Press)

Dutton, L C and Dudhia, J and Catchpole, B and Hodhkiss-Geere, H and Werling, D and Connolly, D J (2018) Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor. Scientific Reports (Nature), 8 (13351).

Soldevila, F and Edwards, J C and Graham, S P and Stevens, L M and Crudginton, B and Crooke, H R and Werling, D and Steinbach, F (2018) Characterisation of the myeloid cell populations' resident in the porcine palatine tonsil. Frontiers in Immunology, 15 (9). p. 1800.

Perivan, A and Bertolini, F and Rothschild, M F and Simpson, K W and Jergens, A E and Allenspach, K and Werling, D (2018) Genome-wide association studies of inflammatory bowel disease in German shepherd dogs. PLoS One, 13 (7). e0200685.

Grierson, S S and Werling, D and Bidewell, C and Williamson, S (2018) Characterisation of porcine circovirus type 2 in porcine circovirus disease cases in England and Wales. VETERINARY RECORD, 182 (1). p. 22.

Werling, D (2018) The immune system is part of a whole-organism regulatory network. RESEARCH IN VETERINARY SCIENCE.

Chen, X and Zhang, S and Cheng, Z R and Cooke, J S and Werling, D and Wathes, D C and Pollott, G E (2017) Polymorphisms in the selectin gene cluster are associated with fertility and survival time in a population of Holstein Friesian cows. PLoS One, 12 (4).

Werling, D and Hope, J and Siddiqui, N and Widdison, S and Russell, C and Sopp, C and Coffey, T J (2017) Subset-specific expression of Toll-like receptors by bovine afferent lymph dendritic cells. Frontiers in Veterinary Science, 4 (44).

Tombacz, K and Mwangi, D and Werling, D and Gibson, A J (2017) Comparison of cellular assays for TLR activation and development of a species-specific reporter cell line for cattle. Innate Immunity, 23 (4). pp. 329-335.

Eley, T S and Patteson, R and Werling, D and Martineau, H M (2017) Exploring the Pathogenesis of Early Stage PCV-2 Infection. JOURNAL OF COMPARATIVE PATHOLOGY, 156 (1). p. 101.

Bilgen, N and Benji, C K and Offord, V and Werling, D and Ertugrul, O (2016) Determination of Genetic Variations of Toll-Like Receptor (TLR) 2, 4, and 6 with Next-Generation Sequencing in Native Cattle Breeds of Anatolia and Holstein Friesian. Diversity, 8 (23).

Peiravan, A and Allenspach, K and Boag, A M and Soutter, F and Holder, A L and Catchpole, B and Kennedy, L J and Werling, D and Procoli, F (2016) Single Nucleotide Polymorphisms in Major histocompatibility class II haplotypes are associated with potential resistance to inflammatory bowel disease in German shepherd dogs. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 182. pp. 101-105.

Lankester, F and Lugelo, A and Werling, D and Mnyambwa, N and Keyyu, J and Kazwala, R and Grant, D and Smith, S and Parameswaran, N and Cleaveland, S and Russell, G and Haig, D (2016) The efficacy of alcelaphine herpesvirus-1 (AlHV-1) immunization with the adjuvants Emulsigen® and the monomeric TLR5 ligand FliC in zebu cattle against AlHV-1 malignant catarrhal fever induced by experimental virus challenge. VETERINARY MICROBIOLOGY, 195. pp. 144-153.

Goh, S and Ngugi, D and Lizundia, R and Hostettler, I and Woods, K and Ballingall, K and MacHugh, N D and Morrison, W I and Weir, W and Shiels, B and Werling, D (2016) Identification of Theileria lestoquardi Antigens Recognized by CD8+ T Cells. PLoS One, 11 (9). e0162571.

Chen, X and Cheng, Z R and Werling, D and Pollott, G E and Salavati, M and Johnson, K F and Khan, F A and Wathes, D C and Zhang, S J (2016) Bovine P-selectin mediates leukocyte adhesion and is highly polymorphic in dairy breeds. RESEARCH IN VETERINARY SCIENCE, 108. pp. 85-92.

Gibson, A J and Woodman, S and Pennelegion, C and Patterson, R and Stuart, E and Hosker, N and Siviter, P and Douglas, C and Whitehouse, J and Wilkinson, W and Pegg, S A and Villarreal-Ramos, B and Werling, D (2016) Differential Macrophage Function in Brown Swiss and Holstein Friesian Cattle. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 181. pp. 15-23.

Jensen, K and Gallagher, I J and Kaliszewska, A and Zhang, C and Abejide, O and Gallagher, M P and Werling, D and Glass, E J (2016) Live and inactivated Salmonella enterica serovar Typhimurium stimulate similar but distinct transcriptome profiles in bovine macrophages and dendritic cells. VETERINARY RESEARCH, 47 (46).

Patterson, R and Eley, T S and Browne, C and Martineau, H M and Werling, D (2015) Oral application of freeze-dried yeast particles expressing the PCV2b Cap protein on their surface induce protection to subsequent PCV2b challenge in vivo. VACCINE, 33 (46). pp. 6199-205.

Chen, X and Cheng, Z R and Zhang, S and Werling, D and Wathes, D C (2015) Combining Genome Wide Association Studies and Differential Gene Expression Data Analyses Identifies Candidate Genes Affecting Mastitis Caused by Two Different Pathogens in the Dairy Cow. Open Journal of Animal Sciences, 5 (4). pp. 358-393.

Patterson, R and Nevel, M and Diaz, A V and Martineau, H M and Demmers, T G M and Browne, C and Mavrommatis, B and Werling, D (2015) Exposure to environmental stressors result in increased viral load and further reduction of production parameters in pigs experimentally infected with PCV2b. VETERINARY MICROBIOLOGY, 177 (3-4). pp. 261-269.

Conejeros, I and Gibson, A J and Werling, D and Munoz-Caro, T and Hermosilla, C and Taubert, A and Burgos, R A (2015) Effect of the synthetic Toll-like receptor ligands LPS, Pam3CSK4, HKLM and FSL-1 in the function of bovine polymorphonuclear neutrophils. Developmental and Comparative Immunology, 52 (2). pp. 215-225.

Schmitz, S and Glanemann, B and Garden, O A and Brooks, H W and Chang, Y M and Werling, D and Allenspach, K (2015) A Prospective, Randomized, Blinded, Placebo-Controlled Pilot Study on the Effect of Enterococcus faecium on Clinical Activity and Intestinal Gene Expression in Canine Food-Responsive Chronic Enteropathy. JOURNAL OF VETERINARY INTERNAL MEDICINE, 29 (2). pp. 533-43.

Menge, C and Loos, D and Bridger, P S and Barth, S and Werling, D and Baljier, G (2015) Bovine macrophages sense Escherichia coli Shiga toxin 1. Innate Immunity, 21 (6). pp. 655-664.

Schmitz, S and Werling, D and Allenspach, K (2015) Effects of Ex-Vivo and In-Vivo Treatment with Probiotics on the Inflammasome in Dogs with Chronic Enteropathy. PLoS One, 10 (3). e0120779.

Lee, A and Kathrani, A and Priestnall, S L and Smith, K C and Werling, D and Allenspach, K (2015) Lack of Correlation between Mucosal Immunoglobulin A-positive Plasma Cell Numbers and TLR5 Genotypes in German Shepherd Dogs with Idiopathic Chronic Enteropathy. JOURNAL OF COMPARATIVE PATHOLOGY, 152 (2-3). pp. 201-5.

Joekel, D and Hinse, P and Raulf, M K and Schicht, S and Baumer, W and Werling, D and Kremmer, E and Strube, C (2015) Vaccination of calves with yeast- and bacterial-expressed paramyosin from the bovine lungworm Dictyocaulus viviparus. Parasite Immunology, 37 (12). pp. 614-623.

Patterson, N J and Günther, J and Gibson, A J and Offord, V and Coffey, T J and Splitter, G and Monk, I and Seyfert, H M and Werling, D (2014) Two TIR-like domain containing proteins in a newly emerging zoonotic Staphylococcus aureus strain sequence type 398 are potential virulence factors by impacting on the host innate immune response. Frontiers in Microbiology, 5 (662).

Zieger, U and Marston, D A and Sharma, R and Chikweto, A and Tiwari, K and Sayyid, M and Louison, B and Goharriz, H and Voller, K and Breed, A C and Werling, D and Fooks, A R and Horton, D L (2014) The Phylogeography of Rabies in Grenada, West Indies, and Implications for Control. PLOS NEGLECTED TROPICAL DISEASES, 8 (10). e3251.

Kathrani, A and Lee, H and White, C and Catchpole, B and Murphy, A M and German, A and Werling, D and Allenspach, K (2014) Association between nucleotide oligomerisation domain two(Nod2) gene polymorphisms and canine inflammatory bowel disease. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 161 (1-2). pp. 32-41.

Tombacz, K and Patterson, R and Grierson, S S and Werling, D (2014) Lack of Genetic Diversity in Newly Sequenced Porcine Circovirus Type 1 Strains Isolated 20 Years Apart. Genome Announcements, 2 (2). e00156-14.

Mavrommatis, B and Offord, V and Patterson, R and Watson, M and Kanellos, T and Steinbach, F and Grierson, S and Werling, D (2014) Global Gene Expression Profiling of Myeloid Immune Cell Subsets in Response to In Vitro Challenge with Porcine Circovirus 2b. PLoS One, 9 (3). e91081.

Kathrani, A and Lee, H and White, C and Catchpole, B and Murphy, A and German, A and Werling, D and Allenspach, K (2014) Association between nucleotide oligomerisation domain two (Nod2) gene polymorphisms and canine inflammatory bowel disease. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 161 (1-2). pp. 32-41.

Osvaldova, A and Woodman, S and Patterson, N J and Offord, V and Mwangi, D and Gibson, A J and Matiasovic, J and Werling, D (2014) Replacement of two aminoacids in the bovine Toll-like receptor 5 TIR domain with their human counterparts partially restores functional response to flagellin. Developmental and Comparative Immunology, 47 (1). pp. 90-94.

Schmitz, S and Henrich, M and Neiger, R and Werling, D and Allenspach, K (2014) Stimulation of Duodenal Biopsies and Whole Blood from Dogs with Food-Responsive Chronic Enteropathy and Healthy Dogs with Toll-Like Receptor Ligands and Probiotic Enterococcus faecium. Scandinavian Journal of Immunology.

Velasova, M and Alarcon, P and Werling, D and Nevel, M and Wieland, B (2013) Effectiveness of porcine circovirus type 2 vaccination in reducing the severity of post-weaning multisystemic wasting syndrome in pigs. VETERINARY JOURNAL, 197 (3). pp. 842-847.

Offord, V and Werling, D (2013) LRRfinder2.0: A webserver for the prediction of leucine-rich repeats. Innate Immunity, 19 (4). pp. 398-402.

Gibson, A J and Coffey, T and Werling, D (2013) Of creatures great and small: the advantages of farm animal models in immunology research. Frontiers in Immunology, 4. p. 124.

Willcocks, S and Offord, V and Seyfert, H M and Coffey, T and Werling, D (2013) Species-specific PAMP recognition by TLR2 and evidence for species-restricted interaction with Dectin-1. Journal of Leukocyte Biology, 94 (3). pp. 449-58.

Patterson, N J and Werling, D (2013) To con protection: TIR-domain containing proteins (Tcp) and innate immune evasion. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 155 (3). pp. 149-154.

Last, V and Williams, A and Werling, D (2012) Inhibition of cytosolic phospholipase A2 prevents prion peptide-induced neuronal damage and co-localisation with Beta III Tubulin. BMC Neuroscience, 13 (1).

Patterson, R and Nerren, J and Kogut, M and Court, P and Villarreal-Ramos, B and Seyfert, H M and Dalby, P and Werling, D (2012) Yeast-surface expressed BVDV E2 protein induces a Th1/Th2 response in naïve T cells. Developmental and Comparative Immunology, 37 (1). pp. 107-114.

Smith, S A and Jann, O C and Haig, D and Russell, G C and Werling, D and Glass, E J and Emes, R D (2012) Adaptive evolution of Toll-like receptor 5 in domesticated mammals. Bmc Evolutionary Biology, 12. Online.

Pagano, S and Satta, N and Werling, D and Offord, V and DeMoerloose, P and Charbonney, E and Hochstrasser, D and Roux-Lombard, P and Vuilleumier, N (2012) Anti-apolipoprotein A-1 IgG in patients with myocardial infarction promotes inflammation through TLR2/CD14 complex. Journal of Internal Medicine, 272 (4). pp. 344-357.

Gibson, A J and Miah, S and Griebel, P and Brownlie, J and Werling, D (2012) Identification of a lineage negative cell population in bovine peripheral blood with the ability to mount a strong type I interferon response. Developmental and Comparative Immunology, 36 (2). pp. 332-341.

Dakin, S G and Dudhia, J and Werling, N J and Werling, D and Abayasekara, D R E and Smith, R K W (2012) Inflamm-Aging and Arachadonic Acid Metabolite Differences with Stage of Tendon Disease. PLoS One, 7 (11). e48978.

Dakin, S G and Werling, D and Hibbert, A and Abayasekara, D R E and Young, N J and Smith, R K W and Dudhia, J (2012) Macrophage Sub-Populations and the Lipoxin A(4) Receptor Implicate Active Inflammation during Equine Tendon Repair. PLoS One, 7 (2). e32333.

Wieland, B and Werling, D and Nevel, M and Grierson, S and Rycroft, A N and Demmers, T G M and Cook, A J C and Done, S H and Armstrong, D and Wathes, C M (2012) Porcine circovirus type 2 infection before and during an outbreak of postweaning multisystemic wasting syndrome on a pig farm in the UK. VETERINARY RECORD, 170 (23). 596+.

Kathrani, A and Holder, A L and Catchpole, B and Alvarez, L and Simpson, K and Werling, D and Allenspach, K (2012) TLR5 Risk-Associated Haplotype for Canine Inflammatory Bowel Disease Confers Hyper-Responsiveness to Flagellin. PLoS One, 7 (1). e30117.

Alarcon, P and Velasova, M and Werling, D and Staerk, K D C and Chang, Y M and Nevel, M and Pfeiffer, D U and Wieland, B (2011) Assessment and quantification of post-weaning multi-systemic wasting syndrome severity at farm level. PREVENTIVE VETERINARY MEDICINE, 98 (1). pp. 19-28.

Gibson, A J and Larsson, J and Bateman, M and Brownlie, J and Werling, D (2011) Bovine Viral Diarrhea Virus Strain- and Cell Type-Specific Inhibition of Type I Interferon Pathways. JOURNAL OF VIROLOGY, 85 (7). pp. 3695-3697.

Kathrani, A and House, A K and Catchpole, B and Murphy, A M and Werling, D and Allenspach, K (2011) Breed-independent toll-like receptor 5 polymorphisms show association with canine inflammatory bowel disease. TISSUE ANTIGENS, 78 (2). pp. 94-101.

Kathrani, A and Schmitz, S and Priestnall, S L and Smith, K C and Werling, D and Garden, O A and Allenspach, K (2011) CD11c(+) Cells are Significantly Decreased in the Duodenum, Ileum and Colon of Dogs with Inflammatory Bowel Disease. JOURNAL OF COMPARATIVE PATHOLOGY, 145 (4). pp. 359-366.

Burgos, R A and Conejeros, I and Hidalgo, M A and Werling, D and Hermosilla, C (2011) Calcium influx, a new potential therapeutic target in the control of neutrophil-dependent inflammatory diseases in bovines. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 143 (1-2). pp. 1-10.

Kathrani, A and Werling, D and Allenspach, K (2011) Canine breeds at high risk of developing inflammatory bowel disease in the south-eastern UK. VETERINARY RECORD, 169 (24). E-pub.

Kwong, L S and Parsons, R and Patterson, R and Coffey, T J and Thonur, L and Chang, J and Russell, G and Haig, D and Werling, D and Hope, J C (2011) Characterisation of antibodies to bovine toll-like receptor (TLR)-2 and cross-reactivity with ovine TLR2. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 139 (2-4). pp. 313-318.

Coffey, T J and Werling, D (2011) Therapeutic targeting of the innate immune system in domestic animals. CELL AND TISSUE RESEARCH, 343 (1). pp. 251-261.

Jungi, T W and Farhat, K and Burgener, I A and Werling, D (2011) Toll-like receptors in domestic animals. CELL AND TISSUE RESEARCH, 343 (1). pp. 107-120.

Allenspach, K and House, A and Smith, K and McNeill, F M and Hendricks, A and Elson-Riggins, J G and Riddle, A L and Steiner, J M and Werling, D and Garden, O A and Catchpole, B and Suchodolski, J S (2010) Evaluation of mucosal bacteria and histopathology, clinical disease activity and expression of Toll-like receptors in German shepherd dogs with chronic enteropathies. VETERINARY MICROBIOLOGY, 146 (3-4). pp. 326-335.

Dunkel, B and Rickards, K J and Werling, D and Page, C P and Cunningham, F M (2010) Evaluation of the effect of phosphodiesterase on equine platelet activation and the effect of antigen challenge on platelet phosphodiesterase activity in horses with recurrent airway obstruction. AMERICAN JOURNAL OF VETERINARY RESEARCH, 71 (5). pp. 534-540.

Metcalfe, H J and Best, A and Kanellos, T and La Radione, R M and Werling, D (2010) Flagellin expression enhances Salmonella accumulation in TLR5-positive macrophages. Developmental and Comparative Immunology, 34 (8). pp. 797-804.

Offord, V and Coffey, T J and Werling, D (2010) LRRfinder: a web application for the identification of leucine-rich repeats and an integrative Toll-like receptor database. Developmental and Comparative Immunology, 34 (10). pp. 1035-1041.

Kathrani, A and House, A K and Catchpole, B and Murphy, A and German, A and Werling, D and Allenspach, K (2010) Polymorphisms in the TLR4 and TLR5 gene are significantly associated with inflammatory bowel disease in German shepherd dogs. PLoS One, 5 (12). e15740.

Wieland, B and Alarcon, P and Velasova, M and Nevel, M and Towrie, H and Pfeiffer, D U and Wathes, C M and Werling, D (2010) Prevalence of endemic pig diseases in England: an overview six months into a large-scale cross-sectional study on Post-Weaning Multi-systemic Wasting Syndrome (PMWS). The Pig Journal, 63. pp. 20-24.

Bridger, P S and Mohr, M and Stamm, I and Frohlich, J and Follmann, W and Birkner, S and Metcalfe, H and Werling, D and Baljer, G and Menge, C (2010) Primary bovine colonic cells: A model to study strain-specific responses to Escherichia coli. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 137 (1-2). pp. 54-63.

Dunkel, B and Rickards, K J and Werling, D and Page, C P and Cunningham, F M (2010) Regulation of equine platelet activation by phosphodiesterase (PDE) and the effect of antigen challenge on platelet PDE in horses with recurrent airway obstruction (RAO). AMERICAN JOURNAL OF VETERINARY RESEARCH, 71 (5). pp. 534-540.

Chaussepied, M and Janski, N and Baumgartner, M and Lizundia, R and Jensen, K and Weri, W and Shiels, B R and Weitzmn, J B and Glass, E J and Werling, D and Langsley, G (2010) TGF-b2 induction regulates invasiveness of Theileria-Transformed Leukocytes and Disease susceptibility. PLoS Pathogens, 6 (11). e1001197.

Widdison, S and Siddiqui, N and Easton, V and Lawrence, F and Ashley, G and Werling, D and Watson, M and Coffey, T (2010) The bovine chemokine receptors and their mRNA abundance in mononuclear phagocytes. BMC Genomics, 11 (439).

Chang, J S and Russell, G C and Jann, O C and Glass, E J and Werling, D and Haig, D (2009) Molecular cloning and characterization of Toll-like receptors 1-10 in sheep. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 127 (1-2). pp. 94-105.

Dunkel, B and Rickards, K J and Werling, D and Page, C P and Cunningham, F M (2009) Neutrophil and platelet activation in equine recurrent airway obstruction is associated with increased neutrophil CD13 expression, but not platelet CD41/61 and CD62P or neutrophil-platelet aggregate formation. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 131 (1-2). pp. 25-32.

Coffey, T J and Werling, D (2009) TB or not TB: A Disease Forgotten, but not Gone. Transboundary and Emerging Diseases, 56 (6-7). p. 203.

Lizundia, R and Werling, D and Langsley, G and Ralph, S A (2009) Theileria Apicoplast as a Target for Chemotherapy. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 53 (3). pp. 1213-1217.

Werling, D and Jann, O C and Offord, V and Glass, E J and Coffey, T J (2009) Variation matters: TLR structure and species-specific pathogen recognition. Trends in Immunology, 30 (3). pp. 124-130.

Alvarez, A J and Endsley, J J and Werling, D and Estes, D M (2009) WC1(+)gamma delta T Cells Indirectly Regulate Chemokine Production During Mycobacterium bovis Infection in SCID-bo Mice. Transboundary and Emerging Diseases, 56 (6-7). pp. 275-284.

Lizundia, R and Sauter, K S and Taylor, G and Werling, D (2008) Host species-specific usage of the TLR4-LPS receptor complex. Innate Immunity, 14 (4). pp. 223-231.

Yamakawa, Y and Pennelegion, C and Willcocks, S and Stalker, A and MacHugh, N and Burt, D and Coffey, T J and Werling, D (2008) Identification and functional characterization of a bovine orthologue to DC-SIGN. Journal of Leukocyte Biology, 83 (6). pp. 1396-1403.

Kaliszewska, A and Jensen, K and Gallagher, M and Werling, D and Glass, E J (2008) MACROPHAGES AND DENDRITIC CELLS HAVE DISTINCT TRANSCRIPTOME PROFILES DURING EARLY INFECTION WITH SALMONELLA ENTERICA SEROVAR TYPHIMURIUM. IMMUNOLOGY, 125 (S1). pp. 83-84.

Jann, O C and Werling, D and Chang, J S and Haig, D and Glass, E J (2008) Molecular evolution of bovine Toll-like receptor 2 suggests substitutions of functional relevance. Bmc Evolutionary Biology, 8 (288).

Kitching, P and Thomson, G and Albrecht, S and Sabara, M and Werling, D (2008) Transboundary disease management: The theory and the practice - The science and the politics. Transboundary and Emerging Diseases, 55 (1). pp. 1-2.

Piercy, J and Werling, D and Coffey, T J (2007) Differential responses of bovine macrophages to infection with bovine-specific and non-bovine specific mycobacteria. TUBERCULOSIS, 87 (5). pp. 415-420.

Werling, D and Coffey, T J (2007) Pattern recognition receptors in companion and farm animals - The key to unlocking the door to animal disease? VETERINARY JOURNAL, 174 (2). pp. 240-251.

Lloyd, D H and Viac, J and Werling, D and Reme, C A and Gatto, H (2007) Role of sugars in surface microbe-host interactions and immune reaction modulation. VETERINARY DERMATOLOGY, 18 (4). pp. 197-204.

Herath, S and Fischer, D P and Werling, D and Williams, E J and Lilly, S T and Dobson, H and Bryant, C E and Sheldon, I M (2006) Expression and function of Toll-like receptor 4 in the endometrial cells of the uterus. Endocrinology, 147 (1). pp. 562-570.

Werling, D and Piercy, J and Coffey, T J (2006) Expression of TOLL-like receptors (TLR) by bovine antigen-presenting cells - Potential role in pathogen discrimination? VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 112 (1-2). pp. 2-11.

Willcocks, S and Yamakawa, Y and Stalker, A and Coffey, T J and Goldammer, T and Werling, D (2006) Identification and gene expression of the bovine C-type lectin Dectin-1. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 113 (1-2). pp. 234-242.

McGuire, K and Jones, M and Werling, D and Williams, J L and Glass, E J and Jann, O C (2006) Radiation hybrid mapping of all 10 characterized bovine Toll-like receptors. ANIMAL GENETICS, 37 (1). pp. 47-50.

Lizundia, R and Chaussepied, M and Huerre, M and Werling, D and Di Santo, J P and Langsley, G (2006) c-Jun NH2-terminal kinase/c-Jun signaling promotes survival and metastasis of B lymphocytes transformed by Theileria. CANCER RESEARCH, 66 (12). pp. 6105-6110.

Dessauge, G and Hilaly, S and Baumgartner, M and Blumen, B and Werling, D and Langsley, G (2005) C-Myc activation by Theileria parasites promotes survival of infected B-lymphocytes. ONCOGENE, 24 (6). pp. 1075-1083.

Werling, D and Hope, JC and Howard, C J and Jungi, T W (2004) Differential production of cytokines, reactive oxygen and nitrogen by bovine macrophages and dendritic cells stimulated with Toll-like receptor agonists. IMMUNOLOGY, 111 (1). pp. 41-52.

Harris, J and Werling, D (2003) Binding and entry of respiratory syncytial virus into host cells and initiation of the innate immune response. CELLULAR MICROBIOLOGY, 5.

Guergnon, J and Chaussepied, M and Sopp, P and Lizundia, R and Moreau, M F and Blumen, B and Werling, D and Howard, C J and Langsley, G (2003) A tumour necrosis factor alpha autocrine loop contributes to proliferation and nuclear factor-kappa B activation of Theileria parva-transformed B cells. CELLULAR MICROBIOLOGY, 5 (10). pp. 709-716.

Werling, D and Collins, R A and Taylor, G and Howard, C J (2002) Cytokine responses of bovine dendritic cells and T cells following exposure to live or inactivated bovine respiratory syncytial virus. Journal of Leukocyte Biology, 72 (2). pp. 297-304.

Conference or Workshop Item

Werling, D (2014) Why is vaccination against mastitis so difficult? In: UNSPECIFIED.

Kathrani, A and Werling, D and Allenspach, K (2011) MUTATIONAL ANALYSIS OF THE TLR5 GENE IN BOXER DOGS WITH INFLAMMATORY BOWEL DISEASE REVEALS NOVEL POLYMORPHISM IN THE LEUCINE RICH REPEAT DOMAIN. In: UNSPECIFIED.

Kathrani, A and House, A K and Werling, D and Catchpole, B and Murphy, A M and Allenspach, K (2011) POLYMORPHISMS IN THE TOLL LIKE RECEPTOR 5 GENE ARE SIGNIFICANTLY ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE IN A POPULATION CONSISTING OF 38 DIFFERENT DOG BREEDS. In: UNSPECIFIED.

Kathrani, A and Werling, D and Holder, A L and Catchpole, B and Allenspach, K (2011) POLYMORPHISMS IN TOLL-LIKE RECEPTOR 5 RESULT IN HYPER-RESPONSIVENESS TO FLAGELLIN. In: UNSPECIFIED.

Allenspach, K and Kathrani, A and House, A K and Holder, A L and Catchpole, B and Werling, D (2011) TOLL-LIKE RECEPTOR 5 MUTATIONS IN GERMAN SHEPHERD DOGS ARE HYPER-RESPONSIVE TO STIMULATION WITH FLAGELLIN. In: UNSPECIFIED.

Kathrani, A and House, A and Werling, D and Smith, K C and Garden, O A and Simbi, B H and Allenspach, K (2010) CD11c POSITIVE DENDRITIC CELLS ARE SIGNIFICANTLY DECREASED IN THE DUODENUM OF DOGS WITH INFLAMMATORY BOWEL DISEASE. In: UNSPECIFIED.

Kathrani, A and House, A K and Werling, D and Catchpole, B and Murphy, A and German, A J and Lee, H and Allenspach, K (2010) OVERDOMINANT SINGLE NUCLEOTIDE POLYMORPHISMS IN THE NUCLEOTIDE OLIGOMERISATION DOMAIN TWO (NOD2) GENE ARE SIGNIFICANTLY ASSOCIATED WITH CANINE INFLAMMATORY BOWEL DISEASE. In: UNSPECIFIED.

Allenspach, K and Suchodolski, J S and McNeill, F M and House, A and Hendricks, A and Xenoulis, P G and Steiner, J M and Werling, D (2008) CHARACTERIZATION OF THE BACTERIAL MICROFLORA AND INNATE IMMUNITY RESPONSE IN GERMAN SHEPHERD DOGS WITH ANTIBIOTIC-RESPONSIVE DIARRHEA. In: UNSPECIFIED.

Bridger, P S and Mohr, M and Frohlich, J and Metcalfe, H and Werling, D and Baljer, G and Menge, C (2008) TOLL-LIKE RECEPTOR EXPRESSION AND BACTERIAL STRAIN DEPENDENT CHEMOKINE RESPONSE IN A PRIMARY BOVINE COLONIC EPITHELIAL CELL CULTURE MODEL. In: UNSPECIFIED.

Sopp, P and Werling, D and Baldwin, C (2007) Cross-reactivity of mAbs to human CD antigens with cells from cattle. In: UNSPECIFIED.

Werling, D and Ruryk, A and Heaney, J and Moeller, E and Brownlie, J (2005) Ability to differentiate between cp and ncp BVDV by microarrays: Towards an application in clinical veterinary medicine? In: UNSPECIFIED.

Other

Woodman, S and Gibson, A J and Garcia, A R and Contreras, G S and Rossen, J W and Werling, D and Offord, V (2015) Structural characterisation of Toll-like receptor 1 (TLR1) and Toll-like receptor 6 (TLR6) in elephant and harbor seals. Elsevier.

Lithgow, P and Takamatsu, H H and Werling, D and Dixon, L and Chapman, D (2014) Correlation of cell surface marker expression with African swine fever virus infection. UNSPECIFIED.

Metcalfe, H J and La Ragione, R M and Smith, D G E and Werling, D (2014) Functional characterisation of bovine TLR5 indicates species-specific recognition of flagellin. UNSPECIFIED.

Schmitz, S and Henrich, M and Neiger, R and Werling, D and Allenspach, K (2013) Comparison of TNF alpha responses induced by Toll-like receptor ligands and probiotic Enterococcus faecium in whole blood and peripheral blood mononuclear cells of healthy dogs. UNSPECIFIED.

Schmitz, S and Hill, S and Werling, D and Allenspach, K (2013) Expression of trefoil factor genes in the duodenum and colon of dogs with inflammatory bowel disease and healthy dogs. UNSPECIFIED.

Schmitz, S and Garden, O G and Werling, D and Allenspach, K (2012) Gene expression of selected signature cytokines of T cell subsets in duodenal tissues of dogs with and without inflammatory bowel disease. UNSPECIFIED.

Burr, S and Thomas, C J and Brownlie, J and Offord, V and Coffey, T J and Werling, D (2012) Potential evidence for biotype-specific chemokine profile following BVDV infection of bovine macrophages. UNSPECIFIED.

Conejeros, I and Patterson, R and Burgos, R A and Hermosilla, C and Werling, D (2011) Induction of reactive oxygen species in bovine neutrophils to CD11b, but not dectin-1-dependent. UNSPECIFIED.

McMahon, L A and House, AK and Catchpole, B and Elson-Riggins, J G and Riddle, A L and Smith, K C and Werling, D and Burgener, I A and Allenspach, K (2010) Expression of Toll-like receptor 2 in duodenal biopsies from dogs with inflammatory bowel disease is associated with severity of disease. UNSPECIFIED.

Sopp, P and Werling, D and Baldwin, C (2008) CROSS-REACTIVITY OF MABS TO HUMAN CD ANTIGENS WITH CELLS FROM CATTLE (VOL 119, PG 106, 2007). UNSPECIFIED.

This list was generated on Wed Jul 8 07:15:30 2020 BST.