Bishop-Bailey, D (2015) Nuclear receptors in vascular biology. Current Atherosclerosis Reports, 17 (5).
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Abstract
Nuclear receptors sense a wide range of steroids and hormones (estrogens, progesterone, androgens, glucocorticoid, and mineralocorticoid), vitamins (A and D), lipid metabolites, carbohydrates, and xenobiotics. In response to these diverse but critically important mediators, nuclear receptors regulate the homeostatic control of lipids, carbohydrate, cholesterol, and xenobiotic drug metabolism, inflammation, cell differentiation and development, including vascular development. The nuclear receptor family is one of the most important groups of signaling molecules in the body and as such represent some of the most important established and emerging clinical and therapeutic targets. This review will highlight some of the recent trends in nuclear receptor biology related to vascular biology.
| Item Type: | Article |
|---|---|
| Article Type: | Review |
| RVC Publication Type: | Review |
| WoS ID: | 000351468300005 |
| DOI: | https://doi.org/10.1007/s11883-015-0507-8 |
| Departments: | Comparative Biomedical Sciences |
| Research Programmes: | Comparative Physiology & Medicine > Cardiovascular and Inflammation Biology and Metabolism |
| Depositing User: | RVC Auto-import |
| Last Modified: | 21 Feb 2020 02:00 |
| URI: | http://researchonline.rvc.ac.uk/id/eprint/9659 |
| Date Deposited: | 12 February 2019 |