Faccenda, D and Gorini, G and Jones, A and Thornton, C and Baracca, A and Solaini, G and Campanella, M (2020) The ATPase Inhibitory Factor 1 (IF1) regulates the expression of the mitochondrial Ca2+ uniporter (MCU) via the AMPK/CREB pathway. Biochimica et biophysica acta. Molecular cell research. p. 118860. ISSN 1879-2596
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Abstract
•IF1 regulates MCU-dependent mitochondrial Ca2+ uptake. •IF1 loss induces MCU upregulation through activation of the AMPK/CREB pathway. •OMA1 depletion restores physiological MCU levels and mitochondrial Ca2+ entry.
| Item Type: | Article |
|---|---|
| RVC Publication Type: | BBA research letter |
| Uncontrolled Keywords: | AMPK and MCU, IF1, calcium, mitochondria |
| Departments: | Comparative Biomedical Sciences |
| SWORD Depositor: | Publications Repository |
| Depositing User: | Publications Repository |
| Last Modified: | 18 Sep 2021 05:59 |
| URI: | https://researchonline.rvc.ac.uk/id/eprint/13074 |
| Date Deposited: | 8 October 2020 |
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