van Hoek, IMJ and Laxalde, J and Connolly, DJ and Rush, JE and Freeman, LM (2020) Echocardiographic, morphometric and biomarker changes in female cats followed from 6 to 24 months of life. Journal of Feline Medicine and Surgery. 1098612X2094368. ISSN 1098-612X
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Abstract
Objectives The aim of the study was to evaluate cardiac size and early growth through echocardiographic, bodyweight (BW), body condition score (BCS), morphometric and biomarker changes in cats followed from 6 to 24 months of age. Methods Twenty-four female European shorthair colony cats were evaluated at birth for BW and at 6, 12, 18 and 24 months of age for BW, BCS, head length (HL) and head width (HW), N-terminal pro B-type natriuretic peptide (NT-proBNP), insulin-like growth factor-1 (IGF-1) and echocardiographic measurements. Results BCS, HW, left ventricular free wall in diastole, left atrium diameter and aortic diameter increased significantly between 6 and 12 months, while BW, HL and interventricular septum in diastole increased significantly between 6, 12 and 18 months, and BW decreased significantly between 18 and 24 months. NT-proBNP decreased significantly between 6 and 12 months. IGF-1 increased significantly between 6 and 12 months but decreased significantly between 12 and 18 months. Conclusions and relevance This study prospectively evaluated changes in echocardiographic measurements, BW, BCS, HL, HW, IGF-1 and NT-proBNP in cats during the first 2 years of life. Results show a comparable change over time for different variables. These findings contribute to the understanding of a possible relationship between cardiac measures and body size from young age through to adulthood.
| Item Type: | Article |
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| DOI: | https://doi.org/10.1177/1098612X20943684 |
| Departments: | Clinical Sciences and Services |
| Depositing User: | RVC Admin |
| Last Modified: | 20 Nov 2020 20:48 |
| URI: | https://researchonline.rvc.ac.uk/id/eprint/12902 |
| Date Deposited: | 17 August 2020 |
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