Interleukin 10 controls the balance between tolerance, pathogen elimination and immunopathology in birds
(2025)
Journal Article
Meunier, D., Corona-Torres, R., Boulton, K., Wu, Z., Ballantyne, M., Glendinning, L., Ahmad, A. A., Borowska, D., Taylor, L., Vervelde, L., del Pozo, J., Vasilogianni, M., Jaramillo-Ortiz, J., Sanchez-Arsuaga, G., Psifidi, A., Tomley, F., Watson, K. A., McGrew, M. J., Stevens, M. P., Blake, D. P., & Hume, D. A. (2025). Interleukin 10 controls the balance between tolerance, pathogen elimination and immunopathology in birds. eLife, https://doi.org/10.7554/elife.106252.1
Effective mucosal immunity in the intestine involves a fine balance between tolerance of the microbiome, recognition and elimination of pathogens, and inflammatory tissue injury. The anti-inflammatory cytokine IL10 regulates these processes in the in...
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