Is there a link between bacteriuria and a reversible encephalopathy in dogs and cats?

Crawford, A (2020) Is there a link between bacteriuria and a reversible encephalopathy in dogs and cats? Journal of Small Animal Practice. ISSN 0022-4510

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Official URL: https://onlinelibrary.wiley.com/journal/17485827

Abstract

Bacteriuria has been associated with abnormal neurological status in humans, particularly the geriatric population. In this report, we review 11 cases (7 dogs and 4 cats) that support an association between bacteriuria and abnormal neurological status in veterinary medicine. The included cases presented with neurological deficits consistent with a diffuse forebrain ± brainstem localisation, in which structural brain disease was excluded with magnetic resonance imaging of the head and cerebrospinal fluid analysis, but in which urine bacteriological culture was positive, and neurological deficits improved or resolved with initiation of antibiosis ± fluid therapy and levetiracetam. While further studies are needed to definitively confirm or refute the link between bacteriuria and a reversible encephalopathy, urine bacteriological culture should be considered in veterinary patients presented with an acute onset forebrain (± brainstem) neuro-anatomical localisation, even in the absence of clinical signs of lower urinary tract inflammation.

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