UK vaccines network: Mapping priority pathogens of epidemic potential and vaccine pipeline developments

Noad, R J and Simpson, K and Fooks, A R and Hewson, R and Gilbert, S C and Stevens, M P and Hosie, M J and Prior, J and Kinsey, A M and Entrican, G and Simpson, A and Whitty, C J M and Carroll, M W (2019) UK vaccines network: Mapping priority pathogens of epidemic potential and vaccine pipeline developments. VACCINE, 37 (43). pp. 6241-6247.

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Abstract

During the 2013–2016 Ebola outbreak in West Africa an expert panel was established on the instructions of the UK Prime Minister to identify priority pathogens for outbreak diseases that had the potential to cause future epidemics. A total of 13 priority pathogens were identified, which led to the prioritisation of spending in emerging diseases vaccine research and development from the UK. This meeting report summarises the process used to develop the UK pathogen priority list, compares it to lists generated by other organisations (World Health Organisation, National Institutes of Allergy and Infectious Diseases) and summarises clinical progress towards the development of vaccines against priority diseases. There is clear technical progress towards the development of vaccines. However, the availability of these vaccines will be dependent on sustained funding for clinical trials and the preparation of clinically acceptable manufactured material during inter-epidemic periods.