Detecting false-positive disease references in veterinary clinical notes without manual annotations

Kennedy, N and Brodbelt, D C and Church, D B and O'Neill, D G (2019) Detecting false-positive disease references in veterinary clinical notes without manual annotations. npj Digital Medicine, 2. p. 33.

[img]
Preview
Text
12105.pdf - Published Version
Available under License Creative Commons Attribution.

Download (682kB) | Preview

Abstract

Clinicians often include references to diseases in clinical notes, which have not been diagnosed in their patients. For some diseases terms, the majority of disease references written in the patient notes may not refer to true disease diagnosis. These references occur because clinicians often use their clinical notes to speculate about disease existence (differential diagnosis) or to state that the disease has been ruled out. To train classifiers for disambiguating disease references, previous researchers built training sets by manually annotating sentences. We show how to create very large training sets without the need for manual annotation. We obtain state-of- the-art classification performance with a bidirectional long short-term memory model trained to distinguish disease references between patients with or without the disease diagnosis in veterinary clinical notes.