Wong, H E and Hedley, J and Stapleton, N and Murphy, B and Priestnall, S L (2018) Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig. JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION.
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Abstract
Odontoameloblastomas (previously incorporated within ameloblastic odontomas) are matrix-producing odontogenic mixed tumors and are closely related in histologic appearance to the 2 other types of matrix-producing odontogenic mixed tumors: odontomas and ameloblastic fibro-odontomas. The presence or absence of intralesional, induced non-neoplastic tissue must be accounted for in the diagnosis. Herein we describe a naturally occurring odontoameloblastoma with extensive chondroid cementum deposition in a guinea pig (Cavia porcellus). Microscopically, the mass featured palisading neoplastic odontogenic epithelium closely apposed to ribbons and rings of a pink dental matrix (dentinoid), alongside extensive sheets and aggregates of chondroid cementum. The final diagnosis was an odontoameloblastoma given the abundance of odontogenic epithelium in association with dentinoid but a paucity of pulp ectomesenchyme. Chondroid cementum is an expected anatomical feature of cavies, and its presence within the odontoameloblastoma was interpreted as a response of the ectomesenchyme of the dental follicle to the described neoplasm. Our case illustrates the inductive capabilities of odontoameloblastomas while highlighting species-specific anatomy that has resulted in a histologic appearance unique to cavies and provides imaging and histologic data to aid diagnosis of these challenging lesions.
| Item Type: | Article |
|---|---|
| RVC Publication Type: | Journal Article |
| DOI: | https://doi.org/10.1177/1040638718794784 |
| Departments: | Clinical Sciences and Services Pathobiology and Population Sciences |
| Depositing User: | RVC Auto-import |
| Last Modified: | 20 Feb 2020 20:28 |
| URI: | http://researchonline.rvc.ac.uk/id/eprint/11714 |
| Date Deposited: | 28 August 2018 |
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