Items where Author is "Williams, A"

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Article

Guardabassi, L and Moodley, A and Williams, A and Stegger, M and Damborg, P and Halliday-Simmonds, I and Butaye, P R (2019) High prevalence of USA300 among clinical isolates of methicillin-resistant Staphylococcus aureus on St. Kitts and Nevis, West Indies. Frontiers in Microbiology, 10. p. 1123.

Bate, C and Williams, A (2018) Monomeric amyloid-ß reduced amyloid-ß oligomer-induced synapse damage in neuronal cultures. NEUROBIOLOGY OF DISEASE, 111. pp. 48-58.

Liao, C and Ashley, N and Diot, A and Morten, K and Phadwal, K and Williams, A and Fearnley, I and Rosser, L and Lowndes, J and Fratter, C and Ferguson, D J P and Vay, L and Quaghebeur, G and Moroni, I and Bianchi, S and Lamperti, C and Downes, S M and Sitarz, K S and Flannery, P J and Carver, J and Dombi, E and East, D and Laura, M and Reilly, M M and Mortiboys, H and Prevo, R and Campanella, M and Daniels, M J and Zeviani, M and Yu-Wai-Man, P and Simon, A K and Votruba, M and Poulton, J (2017) Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations. Neurology, 88 (2). pp. 131-142.

Bate, C and Nolan, W and McHale-Owen, H and Williams, A (2016) Sialic Acid within the Glycosylphosphatidylinositol Anchor Targets the Cellular Prion Protein to Synapses. JOURNAL OF BIOLOGICAL CHEMISTRY, 291 (33). pp. 17093-101.

Bate, C and Nolan, W and Williams, A (2016) Does the tail wag the dog? How the structure of a glycosylphosphatidylinositol anchor affects prion formation. Prion, 10 (2). pp. 127-30.

Osborne, C and West, E and Nolan, W and McHale-Owen, H and Williams, A and Bate, C (2016) Glimepiride protects neurons against amyloid-beta-induced synapse damage. NEUROPHARMACOLOGY, 101. pp. 225-236.

Bate, C and Nolan, W and Williams, A (2016) Glycosylphosphatidylinositols: More than just an anchor? Communicative & Integrative Biology, 9 (2). e1149671-e1149671.

Bate, C and Nolan, W and McHale-Owen, H and Williams, A (2016) Sialic Acid on the Glycosylphosphatidylinositol Anchor Regulates PrP-mediated Cell Signaling and Prion Formation. JOURNAL OF BIOLOGICAL CHEMISTRY, 291 (33). pp. 17093-17101.

Bate, C and Williams, A (2015) a-Synuclein-Induced Synapse Damage in Cultured Neurons Is Mediated by Cholesterol-Sensitive Activation of Cytoplasmic Phospholipase A2. Biomolecules, 5 (1). pp. 178-93.

Bate, C and Williams, A (2015) cAMP-Inhibits Cytoplasmic Phospholipase A(2) and Protects Neurons against Amyloid-beta-Induced Synapse Damage. Biology, 4 (3). pp. 591-606.

Ingham, V and Williams, A and Bate, C (2014) Glimepiride reduces CD14 expression and cytokine secretion from macrophages. JOURNAL OF NEUROINFLAMMATION, 11.

Simmons, C and Ingham, V and Williams, A and Bate, C (2014) Platelet-activating factor antagonists enhance intracellular degradation of amyloid-beta(42) in neurons via regulation of cholesterol ester hydrolases. ALZHEIMERS RESEARCH & THERAPY, 6 (2).

Roberts, V L H and Perkins, J D M and Skarlina, E and Gorvy, D A and Tremaine, W H and Williams, A and McKane, S A and White, I and Knottenbelt, D C (2013) Caudal anaesthesia of the infraorbital nerve for diagnosis of idiopathic headshaking and caudal compression of the infraorbital nerve for its treatment, in 58 horses. EQUINE VETERINARY JOURNAL, 45 (1). pp. 107-110.

Afonso-Barroso, A and Clark, S O and Williams, A and Rosa, G T and Nobrega, C and Silva-Gomes, S and Vale-Costa, S and Ummels, R and Stoker, N and Movahedzadeh, F and Van Der Ley, P and Sloots, A and Cot, M and Appelmelk, B J and Puzo, G and Nigou, J and Geurtsen, J and Appelberg, R (2013) Lipoarabinomannan mannose caps do not affect mycobacterial virulence or the induction of protective immunity in experimental animal models of infection and have minimal impact on in vitro inflammatory responses. CELLULAR MICROBIOLOGY, 15 (4). pp. 660-674.

Last, V and Williams, A and Werling, D (2012) Inhibition of cytosolic phospholipase A2 prevents prion peptide-induced neuronal damage and co-localisation with Beta III Tubulin. BMC Neuroscience, 13 (1).

Bate, C and Williams, A (2012) Clustering of sialylated glycosylphosphatidylinositol anchors mediates PrP-induced activation of cytoplasmic phospholipase A(2) and synapse damage. Prion, 6 (4). pp. 350-353.

Amijee, H and Bate, C and Williams, A and Virdee, J and Jeggo, R and Spanswick, D and Scopes, D I C and Treherne, J M and Mazzitelli, S and Chawner, R and Eyers, C E and Doig, A J (2012) The N-Methylated Peptide SEN304 Powerfully Inhibits A beta(1-42) Toxicity by Perturbing Oligomer Formation. Biochemistry, 51 (42). pp. 8338-8352.

Bate, C and Williams, A (2012) Neurodegeneration Induced by Clustering of Sialylated Glycosylphosphatidylinositols of Prion Proteins. JOURNAL OF BIOLOGICAL CHEMISTRY, 287 (11). pp. 7935-7944.

Gibson, T J and Ridler, A L and Lamb, C R and Williams, A and Giles, S and Gregory, N G (2012) Preliminary evaluation of the effectiveness of captive-bolt guns as a killing method without exsanguination for horned and unhorned sheep. ANIMAL WELFARE, 21. pp. 35-42.

Bate, C and Williams, A (2011) Amyloid-beta-induced Synapse Damage Is Mediated via Cross-linkage of Cellular Prion Proteins. JOURNAL OF BIOLOGICAL CHEMISTRY, 286 (44). pp. 37955-37963.

Bate, C and Williams, A (2011) Ethanol protects cultured neurons against amyloid-beta and alpha-synuclein-induced synapse damage. NEUROPHARMACOLOGY, 61 (8). pp. 1406-1412.

Bate, C and Ingham, V and Williams, A (2011) Inhibition of phospholipase A(2) increased the removal of the prion derived peptide PrP82-146 from cultured neurons. NEUROPHARMACOLOGY, 60 (2-3). pp. 365-372.

Bate, C and Williams, A (2011) Monoacylated Cellular Prion Protein Modifies Cell Membranes, Inhibits Cell Signaling, and Reduces Prion Formation. JOURNAL OF BIOLOGICAL CHEMISTRY, 286 (11). pp. 8752-8758.

Bate, C and Williams, A (2011) The cellular prion protein with a monoacylated glycosylphosphatidylinositol anchor modifies cell membranes, inhibits cell signaling and reduces prion formation. Prion, 5 (2). pp. 65-68.

Bate, C and Gentleman, S and Williams, A (2010) Alpha-synuclein induced synapse damage is enhanced by amyloid-beta. Molecular Neurodegeneration, 5 (55).

Bate, C and Williams, A (2010) Amyloid-beta(1-40) Inhibits Amyloid-beta(1-42) Induced Activation of Cytoplasmic Phospholipase A(2) and Synapse Degeneration. Journal of Alzheimer's Disease, 21 (3). pp. 985-993.

Bate, C and Tayebi, M and Williams, A (2010) Glycosylphosphatidylinositol Anchor Analogues Sequester Cholesterol and Reduce Prion Formation. JOURNAL OF BIOLOGICAL CHEMISTRY, 285 (29). pp. 22017-22026.

Bate, C and Tayebi, M and Williams, A (2010) Phospholipase A(2) inhibitors protect against prion and A beta mediated synapse degeneration. Molecular Neurodegeneration, 5 (13).

Bate, C and Tayebi, M and Salmona, M and Diomede, L and Williams, A (2010) Polyunsaturated Fatty Acids Protect Against Prion-Mediated Synapse Damage In Vitro. Neurotoxicity Research, 17 (3). pp. 203-214.

Bate, C and Tayebi, M and Williams, A (2010) A glycosylphosphatidylinositol analogue reduced prion-derived peptide mediated activation of cytoplasmic phospholipase A(2), synapse degeneration and neuronal death. NEUROPHARMACOLOGY, 59 (1-2). pp. 93-99.

Bate, C and Tayebi, M and Williams, A (2010) The glycosylphosphatidylinositol anchor is a major determinant of prion binding and replication. BIOCHEMICAL JOURNAL, 428. pp. 95-101.

Bate, C and Tayebi, M and Diomede, L and Salmona, M and Williams, A (2009) Glimepiride Reduces the Expression of PrPC, Prevents PrPSc Formation and Protects against Prion Mediated Neurotoxicity. PLoS One, 4 (12). e8221.

Bate, C and Tayebi, M and Williams, A (2008) Cholesterol esterification reduces the neurotoxicity of prions. NEUROPHARMACOLOGY, 54 (8). pp. 1247-1253.

Movahedzadeh, F and Williams, A and Clark, S and Hatch, G and Smith, D and Ten Bokum, A M C and Parish, T and Bacon, J and Stoker, N G (2008) Construction of a severely attenuated mutant of Mycobacterium tuberculosis for reducing risk to laboratory workers. TUBERCULOSIS, 88 (5). pp. 375-381.

Bate, C and Williams, A (2008) Do prion-induced changes in cholesterol trigger neurodegeneration? Future Neurology, 3 (4). pp. 367-370.

Bate, C and Marshall, V and Colombo, L and Diomede, L and Salmona, M and Williams, A (2008) Docosahexaenoic and eicosapentaenoic acids increase neuronal death in response to HuPrP82-146 and A beta 1-42. NEUROPHARMACOLOGY, 54 (6). pp. 934-943.

Bate, C and Tayebi, M and Diomede, L and Salmona, M and Williams, A (2008) Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells. Bmc Biology, 6.

Murray, R and Williams, A and Sheldon, I M (2008) Field investigation of perinatal mortality in Friesian cattle associated with myocardial degeneration and necrosis. REPRODUCTION IN DOMESTIC ANIMALS, 43 (3). pp. 339-345.

Bate, C and Tayebi, M and Williams, A (2008) Ginkgolides protect against amyloid-beta(1-42)-mediated synapse damage in vitro. Molecular Neurodegeneration, 3 (1).

Scurrell, E J and Davies, E and Baines, E and Cherubini, G B and Platt, S and Blakemore, W and Williams, A and Schoniger, S (2008) Neuropathological findings in a Staffordshire bull terrier with L-2-Hydroxyglutaric aciduria. JOURNAL OF COMPARATIVE PATHOLOGY, 138 (2-3). pp. 160-164.

McLennan, N F and Brennan, P M and McNeill, A and Davies, I and Fotheringham, A and Rennison, K A and Ritchie, D and Brannan, F and Head, M W and Ironside, J W and Williams, A and Bell, J E (2008) Prion protein accumulation and neuroprotection in hypoxic brain damage. AMERICAN JOURNAL OF PATHOLOGY, 165 (1). pp. 227-235.

Bate, C and Tayebi, M and Williams, A (2008) Sequestration of free cholesterol in cell membranes by prions correlates with cytoplasmic phospholipase A(2) activation. Bmc Biology, 6.

Bate, C and Rumbold, L and Williams, A (2007) Cholesterol synthesis inhibitors protect against platelet-activating factor-induced neuronal damage. JOURNAL OF NEUROINFLAMMATION, 4. p. 5.

Kempster, S and Bate, C and Williams, A (2007) Simvastatin treatment prolongs the survival of scrapie-infected mice. NEUROREPORT, 18 (5). pp. 479-482.

Wilson, R and Bate, C and Boshuizen, R and Williams, A and Brewer, J (2007) Squalestatin alters the intracellular trafficking of a neurotoxic prion peptide. Bmc Neuroscience, 8.

Bate, C and Williams, A (2007) Squalestatin protects neurons and reduces the activation of cytoplasmic phospholipase A(2) by A beta(1-42). NEUROPHARMACOLOGY, 53 (2). pp. 222-231.

Bate, C and Rumbold, L and Williams, A (2007) Statins reduce the neurotoxicity of platelet-activating factor. JOURNAL OF NEUROINFLAMMATION, 4 (5).

Tayebi, M and Bate, C and Hawke, S and Williams, A (2007) A role for B lymphocytes in anti-infective prion therapies? EXPERT REVIEW OF ANTI-INFECTIVE THERAPY, 5 (4). pp. 631-638.

Bate, C and Kempster, S and Last, V and Williams, A (2006) Interferon-gamma increases neuronal death in response to amyloid-beta(1-42). JOURNAL OF NEUROINFLAMMATION, 3. p. 7.

Bate, C and Kempster, S and Williams, A (2006) Platelet-activating factor antagonists protect amyloid-beta damaged neurons from microglia-mediated death. NEUROPHARMACOLOGY, 51 (2). pp. 173-181.

Bate, C and Kempster, S and Williams, A (2006) Prostaglandin D-2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells. NEUROPHARMACOLOGY, 50 (2). pp. 229-237.

Williams, A and Hatch, G J and Clark, S O and Gooch, K E and Hatch, K A and Hall, G A and Huygen, K and Ottenhoff, T H M and Franken, K L M C and Andersen, P H and Doherty, T M and Kaufmann, S H E and Grode, L and Seiler, P and Martin, C and Gicquel, B and Cole, S T and Brodin, P and Pym, A S and Dalemans, W and Cohen, J and Lobet, Y and Goonetilleke, N and McShane, H and Hill, A and Parish, T and Smith, D and Stoker, N G and Lowrie, D B and Kallenius, G and Svenson, S and Pawowski, A and Blake, K and Marsh, P D (2005) Evaluation of vaccines in the EU TB vaccine cluster using a guinea pig aerosol infection model of tuberculosis. TUBERCULOSIS, 85 (1-2). pp. 29-38.

Bate, C and Boshuizen, R and Williams, A (2005) Microglial cells kill prion-damaged neurons in vitro by a CD14-dependent process. JOURNAL OF NEUROIMMUNOLOGY, 170 (1-2). pp. 62-70.

Bate, C and Williams, A (2004) Detoxified lipopolysaccharide reduces microglial cell killing of prion-infected neurons. NEUROREPORT, 15 (18). pp. 2765-2768.

Brown, A R and Webb, J and Rebus, S and Williams, A and Fazakerley, J K (2004) Identification of up-regulated genes by array analysis in scrapie-infected mouse brains. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 30 (5). pp. 555-567.

Bate, C and Langeveld, J and Williams, A (2004) Manipulation of PrPres production in scrapie-infected neuroblastoma cells. JOURNAL OF NEUROSCIENCE METHODS, 138 (1-2). pp. 217-223.

Nart, P and Williams, A and Thompson, H and Innocent, G T (2004) Morphometry of bovine dilated cardiomyopathy. JOURNAL OF COMPARATIVE PATHOLOGY, 130 (4). pp. 235-245.

Bate, C and Reid, S W J and Williams, A (2004) Phospholipase A(2) inhibitors or platelet-activating factor antagonists prevent prion replication. JOURNAL OF BIOLOGICAL CHEMISTRY, 279 (35). pp. 36405-36411.

Bate, C and Williams, A (2004) Role of glycosylphosphatidylinositols in the activation of phospholipase A(2) and the neurotoxicity of prions. JOURNAL OF GENERAL VIROLOGY, 85 (85). pp. 3797-3804.

Bate, C and Salmona, M and Diomede, L and Williams, A (2004) Squalestatin cures prion-infected neurons and protects against prion neurotoxicity. JOURNAL OF BIOLOGICAL CHEMISTRY, 279 (15). pp. 14983-14990.

Boshuizen, R S and Langeveld, J P M and Salmona, M and Williams, A and Meloen, R H and Langedijk, J P M (2004) An in vitro screening assay based on synthetic prion protein peptides for identification of fibril-interfering compounds. ANALYTICAL BIOCHEMISTRY, 333 (2). pp. 372-380.

Bacon, J and James, B W and Wernisch, L and Williams, A and Morley, K A and Hatch, G J and Mangan, J A and Hinds, J and Stoker, N G and Butcher, P D and Marsh, P D (2004) The influence of reduced oxygen availability on pathogenicity and gene expression in Mycobacterium tuberculosis. TUBERCULOSIS, 84 (3-4). pp. 205-217.

Bate, C and Salmona, M and Williams, A (2004) The role of platelet activating factor in prion and amyloid-beta neurotoxicity. NEUROREPORT, 15 (3). pp. 509-513.

Barret, A and Tagliavini, F and Forloni, G and Bate, C and Salmona, M and Colombo, L and De Luigi, A and Limido, L and Suardi, S and Rossi, G and Auvre, F and Adjou, KT and Sales, N and Williams, A and Lasmezas, C and Deslys, J P (2003) Evaluation of quinacrine treatment for prion diseases. JOURNAL OF VIROLOGY, 77 (15). pp. 8462-8469.

Conference or Workshop Item

Williams, A and Bate, C (2009) LIPID RAFTS, CELL SIGNALLING, PRION FORMATION AND NEURODEGENERATION IN PRION DISEASES. In: UNSPECIFIED.

This list was generated on Mon Feb 24 07:32:08 2020 GMT.