Items where Author is "Wells, D J"

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Wells, D J (2019) What is the level of dystrophin expression required for effective therapy of Duchenne muscular dystrophy? JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, 40 (2). pp. 141-150.

Betts, C A and McClorey, G and Healicon, R and Hammond, S M and Manzano, R and Muses, S and Ball, V and Godfrey, C and Merritt, T M and Westering, T and O'Donovan, L and Wells, K E and Gait, M J and Wells, D J and Tyler, D and Wood, M J (2019) Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment. HUMAN MOLECULAR GENETICS, 28 (3). pp. 396-406.

Hildyard, J C W and Finch, A M and Wells, D J (2019) Identification of qPCR reference genes suitable for normalizing gene expression in the mdx mouse model of Duchenne muscular dystrophy. PLoS One, 14 (1). e0211384.

Willmann, R and Lee, J and Turner, C and Nagaraju, K and Aartsma-Rus, A and Wells, D J and Wagner, K R and Csimma, C and Straub, V and Grounds, M D and De Luca, A (2019) Improving translatability of preclinical studies for neuromuscular disorders: lessons from the TREAT-NMD Advisory Committee for Therapeutics (TACT). Disease Models and Mechanisms, 13.

Gordish-Dressman, H and Willmann, R and Dalle Pazze, L and Kreibich, A and van Putten, M and Heydemann, A and Bogdanik, L and Davies, K and Demonbruen, A and Duan, D and Elsey, D and Fukada, S and Girgenrath, S and Gonzalez, P and Grounds, M and Nichols, A and Partridge, T and Passini, M and Sanarica, F and Schnell, F and Wells, D J and Yokota, T and Young, C and Zhong, Z and Spurney, C and Spencer, M and De Luca, A and Nagaraju, K and Aartsma-Rus, A (2018) "Of Mice and Measures": A Project to Improve How We Advance Duchenne Muscular Dystrophy Therapies to the Clinic. Journal of Neuromuscular Diseases, 5 (4). pp. 407-414.

Wells, D J (2018) Tracking progress: an update on animal models for Duchenne muscular dystrophy. Disease Models and Mechanisms, 11.

Maffioletti, S M and Sarcar, S and Henderson, A B H and Mannhardt, I and Pinton, L and Moyle, L A and Steele-Stallard, H and Cappellari, O and Wells, K E and Ferrari, G and Mitchell, J S and Tyzack, G E and Kotiadis, V N and Khedr, M and Ragazzi, M and Wang, W and Duchen, M R and Patani, R and Zammit, P S and Wells, D J and Eschenhagen, T and Tedesco, F S (2018) Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering. Cell Reports, 23 (3). pp. 899-908.

Hildyard, J C W and Taylor-Brown, F E and Massey, C and Wells, D J and Piercy, R J (2018) Determination of qPCR Reference Genes Suitable for Normalizing Gene Expression in a Canine Model of Duchenne Muscular Dystrophy. Journal of Neuromuscular Diseases, 5 (2). pp. 177-191.

Kondori, N R and Paul, P and Robbins, J P and Liu, K and Hildyard, J C W and Wells, D J and De Belleroche, J S (2018) Focus on the Role of D-serine and D-amino Acid Oxidase in Amyotrophic Lateral Sclerosis/Motor Neuron Disease (ALS). Frontiers in Molecular Biosciences, 5 (8).

Hildyard, J C W and Rawson, F and Harron, R and Riddell, D and Massey, C A and Taylor-Brown, F E and Wells, D J and Piercy, R J (2018) CHARACTERISING THE SKELETAL MUSCLE HISTOLOGICAL PHENOTYPE OF THE DELTAE50-MD DOG, A PRECLINICAL MODEL OF DUCHENNE MUSCULAR DYSTROPHY. Neuromuscular Disorders, 28. S18.

Kondori, N R and Paul, P and Robbins, J P and Liu, K and Hildyard, J C W and Wells, D J and De Belleroche, J S (2017) Characterisation of the pathogenic effects of the in vivo expression of an ALS-linked mutation in D-amino acid oxidase: Phenotype and loss of spinal cord motor neurons. PLoS One, 12. e0188912.

Wells, D J (2017) Systemic MV Gene Therapy Close to Clinical Trials for Several Neuromuscular Diseases. Molecular Therapy, 25 (4). pp. 834-835.

Wells, D J (2017) Designing translationally relevant preclinical studies of new therapeutics. Experimental Physiology, 102 (6). p. 616.

Maffioletti, S M and Sarcar, S and Henderson, A and Mannhardt, I and Pinton, L and Moyle, L A and Steele-Stallard, H and Cappellari, O and Wells, K E and Ragazzi, M and Wang, W and Zammit, P and Wells, D J and Eschenhagen, T and Tedesco, F S (2017) GENERATION OF THREE-DIMENSIONAL HUMAN ARTIFICIAL SKELETAL MUSCLE TISSUE FROM IPS CELLS ENABLES COMPLEX DISEASE MODELLING FOR MUSCULAR DYSTROPHY. HUMAN GENE THERAPY, 28 (12). A2-A2.

Patel, M S and Lee, J and Baz, M and Wells, C E and Bloch, S and Lewis, A and Donaldson, A V and Garfield, B E and Hopkinson, N S and Natanek, A and Man, W D C and Wells, D J and Baker, E H and Polkey, M I and Kemp, P R (2016) Growth differentiation factor-15 is associated with muscle mass in chronic obstructive pulmonary disease and promotes muscle wasting in vivo. Journal of Cachexia, Sarcopenia and Muscle, 7 (4). pp. 436-448.

Lopez-Salesansky, N and Mazlan, N H and Whitfield, L E and Wells, D J and Burn, C C (2016) Olfactory variation in mouse husbandry and its implications for refinement and standardisation: UK survey of non-animal scents. Laboratory Animals, 50 (4). pp. 286-295.

Hildyard, J C W and Lacey, E and Booler, H and Hopkinson, M and Wells, D J and Brown, S C (2016) Transgenic Rescue of the LARGEmyd Mouse: A LARGE Therapeutic Window? PLoS One, 11 (7). e0159853.

Hildyard, J C W and Wells, D J (2016) Investigating synthetic oligonucleotide targeting of miR31 in Duchenne muscular dystrophy. PLoS Currents.

Charles, J P and Cappellari, O and Spence, A J and Hutchinson, J R and Wells, D J (2016) Musculoskeletal Geometry, Muscle Architecture and Functional Specialisations of the Mouse Hindlimb. PLoS One, 11 (4).

Charles, J P and Cappellari, O and Spence, A J and Wells, D J and Hutchinson, J R (2016) Muscle moment arms and sensitivity analysis of a mouse hindlimb musculoskeletal model. JOURNAL OF ANATOMY, 229 (4). pp. 514-535.

Lopez-Salesansky, N and Mazlan, N H and Whitfield, L E and Wells, D J and Burn, C C (2015) Olfaction variation in mouse husbandry and its implications for refinement and standardization: UK survey of animal scents. Laboratory Animals, 50 (5). pp. 362-369.

Lee, J Y and Lori, D and Wells, D J and Kemp, P R (2015) FHL1 activates myostatin signalling in skeletal muscle and promotes atrophy. FEBS Open Bio, 5. pp. 753-762.

Muses, S and Godfrey, C and McClorey, G and Wells, K E and Coursindel, T and Terry, R L and Betts, C and Cappellari, O and Hammond, S and O'Donovan, E and Hildyard, J C W and El Andaloussi, S and Gait, M and Wood, M and Wells, D J (2015) THE PHYSIOLOGICAL CONSEQUENCES OF DIFFERENT LEVELS OF DYSTROPHIN FOLLOWING ANTISENSE BASED EXON-SKIPPING IN THE MDX MOUSE. Neuromuscular Disorders, 25. S312-S313.

Godfrey, C and Muses, S and McClorey, G and Wells, K E and Coursindel, T and Terry, R L and Betts, C and Hammond, S and O'Donovan, L and Hildyard, J C W and El Andaloussi, S and Gait, M J and Wood, M J and Wells, D J (2015) How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse. HUMAN MOLECULAR GENETICS, 24 (15). pp. 4225-4237.

Charles, J P and Cappellari, O and Spence, A and Wells, D J and Hutchinson, J R (2015) DEVELOPING, TESTING AND OPTIMISING A MOUSE HINDLIMB MUSCULOSKELETAL MODEL. FASEB JOURNAL, 29.

Heslop, E and Csimma, C and Straub, V and McCall, J and Nagaraju, K and Wagner, K R and Caizergues, D and Korinthenberg, R and Flanigan, K M and Kaufmann, P and McNeil, E and Mendell, J and Hesterlee, S and Wells, D J (2015) The TREAT-NMD advisory committee for therapeutics (TACT): an innovative de-risking model to foster orphan drug development. ORPHANET JOURNAL OF RARE DISEASES, 10 (49).

Lynn, S and Aartsma-Rus, A and Furlong, P and Goemans, N and De Luca, A and Mayhew, A and McDonald, C and Mercuri, E and Muntoni, F and Pohlschmidt, M and Verschuuren, J and Voit, T and Vroom, E and Wells, D J and Straub, V (2015) Measuring Clinical Effectiveness of Medicinal Products for the Treatment of Duchenne Muscular Dystrophy. Neuromuscular Disorders, 25 (1). pp. 96-105.

Wells, D J (2015) IMPROVING TRANSLATIONAL STUDIES THROUGH BETTER ANIMAL EXPERIMENTS: LESSONS FROM THE HUMAN RARE DISEASE COMMUNITY. Disease Models and Mechanisms.

Wells, D J (2015) Improving translational studies: lessons from rare neuromuscular diseases. Disease Models and Mechanisms, 8 (10). pp. 1175-7.

Bellingham, J and Wells, D J and Foster, R G (2015) In silico characterisation and chromosomal localisation of human RRH (peropsin) – implications for opsin evolution. BMC Genomics, 4 (1). p. 3.

Wells, D J and Heslop, E and Csimma, C and Straub, V and McCall, J and Nagaraju, K and Wagner, K and Caizergues, D and Korinthenberg, R and Flanigan, K and Mendell, J and Kelly, M and Kaufmann, P and McNeil, E and Robertson, A and Johnston, L and Bushby, K (2015) THE TREAT-NMD ADVISORY COMMITTEE FOR THERAPEUTICS (TACT): AN INNOVATIVE DE-RISKING MODEL TO FOSTER ORPHAN DRUG DEVELOPMENT. Neuromuscular Disorders, 25. S271-S271.

Terry, R L and Kaneb, H M and Wells, D J (2014) Poloxomer 188 Has a Deleterious Effect on Dystrophic Skeletal Muscle Function. PLoS One, 9 (3). e91221.

Hildyard, J C W and Wells, D J (2014) Identification and validation of quantitative PCR reference genes suitable for normalising expression in normal and dystrophic cell culture models of myogenesis. PLoS Currents, 6.

Hildyard, J C W and Wells, D J (2014) Identification and validation of quantitative PCR reference genes suitable for normalizing expression in normal and dystrophic cell culture models of myogenesis.

van Putten, M and Terry, R L and Hulsker, M and Wells, K E and Aartsma-Rus, A and Wells, D J (2014) MUSCLE PHYSIOLOGY PROPERTIES OF MOUSE MODELS FOR DUCHENNE MUSCULAR DYSTROPHY. Neuromuscular Disorders, 24 (9-10). pp. 819-820.

Mazlan, N H and Lopez-Salesansky, N and Burn, C C and Wells, D J (2014) Mouse identification methods and potential welfare issues: a survey of current practice in the UK. Animal Technology and Welfare, 13 (1). pp. 1-10.

Aartsma-Rus, A and Ferlini, A and Goemans, N and Pasmooij, A M G and Wells, D J and Bushby, K and Vroom, E and Balabanov, P (2014) Translational and Regulatory Challenges for Exon Skipping Therapies. HUMAN GENE THERAPY, 25 (10). pp. 885-892.

Whitmore, C and Fernandez-Fuente, M and Booler, H and Parr, C and Kavishwar, M and Ashraf, A and Lacey, E and Kim, J and Terry, R and Ackroyd, M R and Wells, K E and Muntoni, F and Wells, D J and Brown, S C (2014) The transgenic expression of LARGE exacerbates the muscle phenotype of dystroglycanopathy mice. HUMAN MOLECULAR GENETICS, 23 (7). pp. 1842-1855.

Fernandez-Fuente, M and Kim, J and Wells, D J and Brown, S C (2013) ASSESSMENT OF NEUROMUSCULAR JUNCTION ABNORMALITIES INDUCED BY ALPHA-DYSTROGLYCAN GLYCOSYLATION DEFECTS. Neuromuscular Disorders, 23 (9-10). pp. 781-782.

van Putten, M and Terry, R and Hulsker, M and Wells, K E and Aartsma-Rus, A and Wells, D J (2013) MUSCLE PHYSIOLOGY PROPERTIES OF MOUSE MODELS FOR DUCHENNE MUSCULAR DYSTROPHY. Neuromuscular Disorders, 23 (9-10). p. 840.

Miller, G and Moore, C J and Terry, R L and La Riviere, T and Mitchell, A and Piggott, R and Dear, T N and Wells, D J and Winder, S J (2012) Preventing phosphorylation of dystroglycan ameliorates the dystrophic phenotype in mdx mouse. HUMAN MOLECULAR GENETICS, 21 (20). pp. 4508-4520.

Browning, R J and Mulvana, H and Tang, M X and Hajnal, J V and Wells, D J and Eckersley, R J (2012) Effect of albumin and dextrose concentration on ultrasound and microbubble mediated gene transfection in vivo. ULTRASOUND IN MEDICINE AND BIOLOGY, 38 (6). pp. 1067-77.

Wells, K E and Muses, S and Ruberg, A and Terry, R and Shihab, N K and Wells, D J (2012) OVER EXPRESSION OF THE LARGE TRANSGENE EXACERBATES MUSCLE PATHOLOGY IN THE MDX MOUSE. Neuromuscular Disorders, 22 (9-10). p. 813.

Muses, S and Jones, H and Wells, D J (2012) RESTORING THE READING FRAME IN LARGE DMD DUPLICATION MUTATIONS RESULTS IN DYSTROPHIN EXPRESSION IN VIVO. Neuromuscular Disorders, 22 (9-10). p. 857.

Song, W and Dyer, E and Stuckey, D J and Copeland, O and Leung, M C and Bayliss, C and Messer, A and Wilkinson, R and Tremoleda, J L and Schneider, M D and Harding, S E and Redwood, C S and Clarke, K and Nowak, K and Monserrat, L and Wells, D J and Marston, S B (2011) Molecular Mechanism of the E99K Mutation in Cardiac Actin (ACTC Gene) That Causes Apical Hypertrophy in Man and Mouse. JOURNAL OF BIOLOGICAL CHEMISTRY, 286 (31). 27582–27593.

Malerba, A and Graham, I and Sharp, P and Popplewell, L and Foster, K and Wells, D J and Dickson, G (2011) Chronic Systemic Therapy With Low-dose Morpholino Oligomers Ameliorates the Pathology and Normalizes Locomotor Behavior in mdx Mice. Molecular Therapy, 19 (2). pp. 345-54.

Soloviev, V Y and McGinty, J and Stuckey, D W and Laine, R and Wylezinska-Arridge, M and Wells, D J and Sardini, A and Hajnal, J V and French, P M W and Arridge, S R (2011) Forster resonance energy transfer imaging in vivo with approximated radiative transfer equation. Applied Optics, 50 (36). pp. 6583-6590.

McGinty, J and Stuckey, D W and Solovjev, V Y and Wylezinska-Arridge, M and Wells, D J and Arridge, S R and P M W, French and Hajnal, J V and Sardini, A (2011) In vivo fluorescence lifetime tomography of a FRET probe expressed in mouse. Biomedical Optics Express, 2 (7). pp. 1907-1917.

Browning, R J and Mulvana, H and Tang, M X and Hajnal, J V and Wells, D J and Eckersley, R J (2011) Influence of needle gauge on in vivo ultrasound and microbubble-mediated gene transfection. ULTRASOUND IN MEDICINE AND BIOLOGY, 37 (9). pp. 1531-1537.

Kaneb, H M and Sharp, P S and Rahmani-Kondori, N and Wells, D J (2011) Metformin Treatment Has No Beneficial Effect in a Dose-Response Survival Study in the SOD1(G93A) Mouse Model of ALS and Is Harmful in Female Mice. PLoS One, 6 (9). e24189.

Muntoni, F and Torelli, S and Wells, D J and Brown, S C (2011) Muscular dystrophies due to glycosylation defects: diagnosis and therapeutic strategies. Current Opinion in Neurology, 24 (5). pp. 437-442.

Muses, S and Morgan, J E and Wells, D J (2011) A New Extensively Characterised Conditionally Immortal Muscle Cell-Line for Investigating Therapeutic Strategies in Muscular Dystrophies. PLoS One, 6 (9). e24826.

Sharp, P S and Bye-a-Jee, H and Wells, D J (2011) Physiological Characterization of muscle strength with variable levels of Dystrophin Restoration in mdx Mice following local antisense therapy. Molecular Therapy, 19 (1). pp. 165-171.

Muses, S and Morgan, J E and Wells, D J (2011) Restoration of dystrophin expression using the Sleeping Beauty transposon. PLoS Currents, 3.

Brockington, M A and Torelli, S and Sharp, P S and Liu, K and Cirak, S and Brown, S C and Wells, D J and Muntoni, F (2010) Transgenic Overexpression of LARGE Induces alpha-Dystroglycan Hyperglycosylation in Skeletal and Cardiac Muscle. PLoS One, 5 (12). e14434.

Wells, D J (2010) Electroporation and ultrasound enhanced non-viral gene delivery in vitro and in vivo. Cell Biology and Toxicology, 26 (1). pp. 21-28.

Song, W and Dyer, E and Stuckey, D and Leung, M-C and Memo, M and Mansfield, C and Ferenczi, M and Liu, K and Redwood, C and Nowak, K and Harding, S and Clarke, K and Wells, D J and Marston, S (2010) Investigation of a transgenic mouse model of familial dilated cardiomyopathy. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 49 (3). pp. 380-389.

Van Der Weerd, L and Tariq Akbar, M and Aron Badin, R and Valentim, L M and Thomas, D L and Wells, D J and Latchman, D S and Gadian, D G and Lythgoe, M F and De Belleroche, J S (2010) Overexpression of heat shock protein 27 reduces cortical damage after cerebral ischemia. Journal of Cerebral Blood Flow & Metabolism, 30 (4). pp. 849-56.

Kinali, M and Arechavala-Gomeza, V and Feng, L and Cirak, S and Hunt, D and Adkin, C and Guglieri, M and Ashton, E and Abbs, S and Nihoyannopoulos, P and Garralda, M E and Rutherford, M and McCulley, C and Popplewell, L and Graham, I R and Dickson, G and Wood, M J and Wells, D J and Wilton, S D and Kole, R and Staub, V and Bushby, K and Sewry, C and Morgan, J E and Muntoni, F (2009) Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-esclation, proof-of-concept study. Lancet Neurology, 8 (10). pp. 918-28.

Dai, T and Patel-Chamberlin, M and Natarajan, R and Todorov, I and Ma, J and LaPage, J and Phillips, L and Nast, C C and Becerra, D and Chuang, P and Tong, L and De Belleroche, J and Wells, D J and Wang, Y and Adler, S G (2009) Heat shock protein 27 overexpression mitigates cytokine-induced islet apoptosis and streptozotocin-induced diabetes. Endocrinology, 150 (7). pp. 3031-9.

Rayner, K and Sun, J and Chen, Y X and McNulty, M and Simard, T and Zhao, X and Wells, D J and de Belleroche, J and O'Brien, E R (2009) Heat shock protein 27 protects against atherogenesis via an Estrogen-Dependent Mechanism: Role of Selective Estrogen Receptor Beta Modulation. Arteriosclerosis, Thrombosis, and Vascular Biology, 29 (11). pp. 1751-6.

Chen, S W C and Kim, M and Kim, M and Song, J H and Park, S W and Wells, D J and De Belleroche, J and D'Agati, V C and Lee, H T (2009) Mice that overexpresses human heat shock protein 27 have increased renal injury following ischemia reperfusion. Kidney International, 75 (5). pp. 499-510.

Alter, J and Sennoga, C A and Lopes, D and Eckserley, R J and Wells, D J (2009) Microbubble stability is a major determinant of the efficiency of ultrasound and microbubble mediated in vivo gene transfer. ULTRASOUND IN MEDICINE AND BIOLOGY, 35 (6). pp. 976-84.

Foster, H and Sharp, P and Trollet, C and Athanasopoulos, T and Graham, I and Foster, K and Wells, D J and Dickson, G (2008) Codon optimisation of microdystrophin improves expression and physiological outcome in dystrophic mdx mice following AAV2/8 gene transfer. Molecular Therapy, 16 (11). pp. 1825-32.

Rayner, K and Chen, Y-X and McNulty, M and Simard, T and Zhao, X and Wells, D J and de Belleroche, J and O'Brien, E R (2008) Extracellular Release of the Atheroprotective Heat Shock Protein 27 Is Mediated by Estrogen and Competitively Inhibits acLDL Binding to Scavenger Receptor-A. CIRCULATION RESEARCH, 103 (2). pp. 133-141.

Sharp, P A and Akbar, T and Bouri, S and Senda, A and Joshi, K and Chen, H J and Latchman, D S and Wells, D J and De Belleroche, J (2008) Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression. NEUROBIOLOGY OF DISEASE, 30 (1). pp. 42-55.

Book Section

Terry, R L and Wells, D J (2016) Histopathological Evaluation of Skeletal Muscle with Specific Reference to Mouse Models of Muscular Dystrophy. In: Current Protocols in Mouse Biology. Wiley, pp. 343-363. ISBN 9780470942390

Wells, D J (2011) Animal welfare and the 3Rs in European biomedical research. In: UNSPECIFIED UNSPECIFIED, pp. 14-16.

Wells, D J (2010) Genetically modified animals and pharmacological research. In: UNSPECIFIED UNSPECIFIED, pp. 213-26.

Conference or Workshop Item

Stenler, S and Andaloussi, S E L and Hammond, S and Goyenvalle, A and Wwood, M J A and Wells, D J and Lundin, K E and Smith, C I E and Blomberg, P (2015) MICRO-MINICIRCLE VECTORS FOR SPLICE-SWITCHING IN MOUSE MODEL OF DUCHENNE MUSCULAR DYSTROPHY. In: UNSPECIFIED.

Hawkins, P and Littlefair, P and Gollege, H and Richardson, C and Allden, S and Boden, T and Hendrie, C and Wells, D J and Osborne, N and Hutchinson, M and Ryder, S and Jennings, M and Hubrecht, R (2014) Report of the 2013 RSPCA/UFAW Rodent Welfare Group Meeting. In: UNSPECIFIED.

Wells, K E and Muses, S and Terry, R L and Wood, M J and Gait, M J and Wells, D J (2013) PEPTIDE-PMO INDUCED EXON-SKIPPING RESTORES MUSCLE PHYSIOLOGY IN THE MDX MOUSE. In: UNSPECIFIED.

Whitmore, C and Booler, H and Terry, R and Ashraf, A and Parr, C and Ackroyd, M R and Fernandez-Fuente, M and Muntoni, F and Wells, D J and Brown, S C (2012) ASSESSING THE THERAPEUTIC POTENTIAL OF LARGE IN A MOUSE MODEL FOR THE LIMB GIRDLE MUSCULAR DYSTROPHIES. In: UNSPECIFIED.

Rahmani-Kondori, N and de Belleroche, J and Wells, D J (2012) INVESTIGATING THE EFFECTS OF DAO TRANSGENES ON THE SOD1(G93A) MOUSE MODEL OF AMYOTROPHIC LATERAL SCLEROSIS (ALS). In: UNSPECIFIED.

Heslop, E and Bushby, K and Csimma, C and Straub, V and Wells, D J (2012) MOVING FORWARD WITH TACT: 2 YEARS ON. In: UNSPECIFIED.

Terry, R L and Kaneb, H M and Wells, D J (2012) POLOXOMER 188 HAS A DELETERIOUS EFFECT ON SKELETAL MUSCLE FUNCTION IN THE MDX MOUSE. In: UNSPECIFIED.

Terry, R L and Wells, D J (2012) TREATMENT WITH ORAL METFORMIN IMPROVES MUSCLE FUNCTION IN MDX MICE. In: UNSPECIFIED.

Muses, S and Jones, H and Wells, D J (2011) ARE LARGE-IN-FRAME DUPLICATIONS OF DYSTROPHIN FUNCTIONAL? In: UNSPECIFIED.

Whitmore, C and Ackroyd, M R and Muses, S and Ashraf, A and Muntoni, F and Brown, S C and Wells, D J (2011) ASSESSING THE THERAPEUTIC POTENTIAL OF LARGE IN A NEW MOUSE MODEL OF DYSTROGLYCANOPATHY. In: UNSPECIFIED.

Cirak, S and Arechavala-Gomeza, V and Guglieri, M and Feng, L and Torelli, S and Anthony, K and Garralda, M E and Wells, D J and Dickson, G and Wood, M J A and Wilton, S D and Straub, V and Shrewsbury, S B and Sewry, C and Morgan, J E and Bushby, K and Muntoni, F (2011) EXON SKIPPING AND DYSTROPHIN RESTORATION IN DUCHENNE MUSCULAR DYSTROPHY PATIENTS AFTER SYSTEMIC PHOSPHORODIAMIDATE MORPHOLINO OLIGOMER TREATMENT. In: UNSPECIFIED.

Wells, D J (2011) OUTCOME MEASURES IN THE MDX MOUSE. In: UNSPECIFIED.

Wells, D J (2010) MAKING SENSE IN DUCHENNE MUSCULAR DYSTROPHY. In: UNSPECIFIED.

Terry, R L and Hasan, N and Wells, D J (2010) MDX MICE SHOW CHANGES IN MUSCLE FIBER PROFILE NUMBER WITH AGE. In: UNSPECIFIED.

Other

Wells, D J Chronic administration of low and high doses of phosphorodiamidate morpholino oligomer ameliorates the dystrophic phenotype in mdx mice. UNSPECIFIED.

Wells, D J A Novel Conditionally Immortal Muscle Cell-line for Investigating Therapeutic Strategies in Muscle Cell Research. UNSPECIFIED.

Wells, D J Systemic administration of the morpholino antisense oligomer AVI-4658 induces exon skipping and dystrophin expression in Duchenne Muscular Dystrophy. UNSPECIFIED.

This list was generated on Sat Feb 22 07:26:33 2020 GMT.