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Welcome to RVC Repository

RVC Research Online is a repository of the research outputs produced by staff from the Royal Veterinary College (RVC). The aims of the repository are (i) to provide an institutional archive of RVC's research outputs, (ii) to provide access to these outputs and support open science, and (iii) to increase the reach and impact of RVC's research.

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Latest Additions

Stable Sulforaphane Targets the Early Stages of Osteoclast Formation to Engender a Lasting Functional Blockade of Osteoclastogenesis (2024)
Journal Article
Louka, P., Orriss, I. R., & Pitsillides, A. A. (2024). Stable Sulforaphane Targets the Early Stages of Osteoclast Formation to Engender a Lasting Functional Blockade of Osteoclastogenesis. Cells, 13(2), https://doi.org/10.3390/cells13020165

Sulforaphane, the native but unstable form of SFX-01, is an antioxidant that activates the NRF2 and inhibits the NF-KB pathways to achieve its actions. Resolving the mechanism(s) by which SFX-01 serves to control the various osteoclastogenic stages m... Read More about Stable Sulforaphane Targets the Early Stages of Osteoclast Formation to Engender a Lasting Functional Blockade of Osteoclastogenesis.

Modelling flock heterogeneity in the transmission of peste des petits ruminants virus and its impact on the effectiveness of vaccination for eradication (2023)
Journal Article
Savagar, B., Jones, B. A., Arnold, M., Walker, M., & Fournié, G. (2023). Modelling flock heterogeneity in the transmission of peste des petits ruminants virus and its impact on the effectiveness of vaccination for eradication. Epidemics, 45, https://doi.org/10.1016/j.epidem.2023.100725

Peste des petits ruminants (PPR) is an acute infectious disease of small ruminants targeted for global eradication by 2030. The Global Strategy for Control and Eradication (GSCE) recommends mass vaccination targeting 70% coverage of small ruminant po... Read More about Modelling flock heterogeneity in the transmission of peste des petits ruminants virus and its impact on the effectiveness of vaccination for eradication.

Risk factors for COVID-19 mortality in hospitalized patients in Bolivia (2023)
Journal Article
Limachi-Choque, J., Guitian, J., Leyns, C., Guzman-Rivero, M., & Eid, D. (2023). Risk factors for COVID-19 mortality in hospitalized patients in Bolivia. IJID International Journal for Infectious Diseases Regions, 9, 95-101. https://doi.org/10.1016/j.ijregi.2023.10.002

Objectives This study aimed to ascertain which factors are associated with higher risk of mortality among hospitalized COVID-19 Bolivian patients. Methods This retrospective observational study assessed risk factors associated with mortality in patie... Read More about Risk factors for COVID-19 mortality in hospitalized patients in Bolivia.

Prevalence and Types of Extended-Spectrum β-Lactamase-Producing Bacteria in Retail Seafood (2023)
Journal Article
Pearce, R., Conrady, B., & Guardabassi, L. (2023). Prevalence and Types of Extended-Spectrum β-Lactamase-Producing Bacteria in Retail Seafood. Foods, 12(16), https://doi.org/10.3390/foods12163033

Objectives: To assess prevalence and types of extended-spectrum β-lactamase (ESBL)-producing bacteria in retail seafood. Methods: A literature review was completed according to international guidelines for systematic reviews, except for being perform... Read More about Prevalence and Types of Extended-Spectrum β-Lactamase-Producing Bacteria in Retail Seafood.