Items where Author is "Ludtmann, M H R"

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Soutar, M P M and Kempthorne, L and Annuario, E and Luft, C and Wray, S and Ketteler, R and Ludtmann, M H R and Plun-Favreau, H (2019) FBS/BSA media concentration determines CCCP’s ability to depolarize mitochondria and activate PINK1-PRKN mitophagy. Autophagy.

Ludtmann, M H R and Kostic, M and Horne, A and Gandhi, S and Sekler, I and Abramov, A Y (2019) LRRK2 deficiency induced mitochondrial Ca2+ efflux inhibition can be rescued by Na+/Ca2+/Li+ exchanger upregulation. CELL DEATH & DISEASE, 10. p. 265.

Jadiya, P and Kolmetzky, D W and Tomar, D and Di Meco, A and Lombardi, A A and Lambert, J P and Luongo, T S and Ludtmann, M H R and Praticò, D and Elrod, J W (2019) Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer’s disease. Nature Communications, 10 (3885).

Ludtmann, M H R and Angelova, P R and Horrocks, M H and Choi, M L and Rodrigues, M and Baev, A Y and Berezhnov, A V and Yao, Z and Little, D and Banushi, B and Al-Menhali, A S and Ranasinghe, R T and Whiten, D R and Yapom, R and Dolt, K S and Devine, M J and Gissen, P and Kunath, T and Jaganjac, M and Pavlov, E V and Klenerman, D and Abramov, A Y and Gandhi, S (2018) a-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease. Nature Communications, 9. p. 2293.

Ludtmann, M H R and Abramov, A Y (2018) Mitochondrial calcium imbalance in Parkinson's disease. Neuroscience Letters, 663. p. 8690.

Ludtmann, M H R (2018) Direct interaction of oligomeric alpha-synuclein with ATP synthase leads to mitochondrial PTP opening in Parkinson’s disease. UNSPECIFIED.

Manole, A and Jaunmuktane, Z and Hargreaves, I and Ludtmann, M H R and Pandraud, A and Salpietro, V and Pope, S and Horga, A and Scalco, R S and Li, A and Ashokkumar, B and Lourenço, C M and Horvath, R and Chinnery, P F and Toro, C and Singleton, A B and Abramov, A and Muntoni, F and Hanna, F G and Reilly, M M and Revesz, T and Kullman, N D M and Jepson, J E C and Houlden, H (2017) Clinical, pathological and functional characterization of riboflavin-responsive neuropathy. BRAIN, 140 (11). pp. 2820-2837.

Iljina, M and Hong, L and Horrocks, M H and Ludtmann, M H R and Hughes, C D and Choi, M L and Ruggeri, F S and Guilliams, T and Buell, A K and Gandhi, S and Bryant, C E and Vendruscolo, M and Knowles, T P J and Dobson, C M and De Genst, E and Klenerman, D (2017) Nanobodies raised against monomeric a-synuclein inhibit fibril-formation and destabilize toxic oligomeric species of a-synuclein. BMC Biology, 15 (57).

Ludtmann, M H R and Arber, C and Bartolome, F and De Vicente, M and Preza, E and Carro, E and Houlden, H and Gandhi, S and Wray, S and Abramov, A Y (2017) Mutations in valosin-containing protein (VCP) decrease ADP/ATP translocation across the mitochondrial membrane and impair energy metabolism in human neurons. JOURNAL OF BIOLOGICAL CHEMISTRY, 292 (21). pp. 8907-8917.

Ludtmann, M H R and Angelova, P R and Ninkina, N and Gandhi, S and Buchman, V L and Abramov, A Y (2016) Monomeric alpha-synuclein exerts a physiological role in brain ATP synthase. JOURNAL OF NEUROSCIENCE, 36 (41). pp. 10510-10521.

Deas, E and Cremades, N and Angelova, P R and Ludtmann, M H R and Yao, Z and Chen, S and Horrocks, M H and Banushi, B and Little, D and Devine, M J and Gissen, P and Klenerman, D and Dobson, C M and Wood, N W and Gandhi, S and Abramov, A Y (2016) Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease. Antioxidants & Redox Signaling, 24 (7). pp. 376-91.

Angelova, P R and Ludtmann, M H R and Horrocks, M H and Negoda, A and Cremades, N and Klenerman, D and Dobson, C M and Wood, N W and Pavlov, E V and Gandhi, S and Abramov A Y (2016) Ca2+ is a key factor in a-synuclein-induced neurotoxicity. Journal of Cell Science, 129 (9). pp. 1792-801.

Ludtmann, M H R and Abramov, A Y (2016) Protein Misfolding and Aggregation: Implications for Mitochondrial Dysfunction and Neurodegeneration. In: Reeve A., Simcox E., Duchen M., Turnbull D. (eds) Mitochondrial Dysfunction in Neurodegenerative Disorders. In: UNSPECIFIED UNSPECIFIED.

Kostic, M and Ludtmann, M H R and Bading, H and Hershfinkel, M and Steer, E and Chu, C T and Abramov, A Y and Sekler, I (2015) PKA Phosphorylation of NCLX Reverses Mitochondrial Calcium Overload and Depolarization, Promoting Survival of PINK1-Deficient Dopaminergic Neurons. Cell Reports, 13 (2). pp. 376-386.

Reeve, A K and Ludtmann, M H R and Angelova, P R and Simcox, E M and Horrocks, M H and Klenerman, D and Gandhi, S and Turnbull, D M and Abramov, A Y (2015) Aggregated a-synuclein and complex I deficiency: exploration of their relationship in differentiated neurons. CELL DEATH & DISEASE, 6. e1820.

Mencacci, N E and Rubio-Agusti, I and Zdebik, A and Asmus, F and Ludtmann, M H R and Ryten, M and Plagnol, V and Hauser, A K and Bandres-Ciga, S and Bettencourt, C and Forabosco, P and Hughes, D and Soutar, M M and Peall, K and Morris, H R and Trabzuni, D and Tekman, M and Stanescu, H C and Kleta, R and Carecchio, M and Zorzi, G and Nardocci, N and Garavaglia, B and Lohmann, E and Weissbach, A and Klein, C and Hardy, J and Pittman, A M and Foltynie, T and Abramov, A Y and Gasser, T and Bhatia, K P and Wood, N W (2015) A Missense Mutation in KCTD17 Causes Autosomal Dominant Myoclonus-Dystonia. American Journal of Human Genetics, 96 (6). pp. 938-47.

Waheed, A and Ludtmann, M H R and Pakes, N and Robery, S and Kuspa, A and Dinh, C and Baines, D and Williams, R S and Carew, M A (2014) Naringenin inhibits the growth of Dictyostelium and MDCK-derived cysts in a polycystin-2 (TRPP2)-dependent manner. BRITISH JOURNAL OF PHARMACOLOGY, 171. pp. 2659-70.

Ludtmann, M H R and Otto, G P and Schilde, C and Chen, Z-H and Allan, C Y and Brace, S and Beesley, P W and Kimmel, A R, Fisher, P and Killick, R and Williams, R S B (2014) An ancestral non-proteolytic role for presenilin proteins in multicellular development of the social amoeba Dictyostelium discoideum. Journal of Cell Science, 127 (7). pp. 1576-1584.

Ludtmann, M H R and Angelova, P R and Zhang, Y and Abramov, A Y and Dinkova-Kostova, A T (2014) Nrf2 impacts the efficiency of mitochondrial fatty acid oxidation. BIOCHEMICAL JOURNAL, 457 (3). pp. 415-424.

Neary, M T and Ng K E and Ludtmann, M H R and Hall, A R and Piotrowska, I and Ong, S B and Hausenloy, D J and Mohun, T J and Abramov, A Y and Breckenridge, R A (2014) Hypoxia signaling controls postnatal changes in cardiac mitochondrial morphology and function. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 74. pp. 340-352.

This list was generated on Wed Sep 18 07:17:30 2019 BST.