HIV and schistosomiasis co-infection in African children

Bustinduy, A and King, C and Scott, J and Appleton, S and Sousa-Figueiredo, J C and Betson, M and Stothard, J R (2014) HIV and schistosomiasis co-infection in African children. Lancet Infectious Disease, 14 (7). pp. 640-649.

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Abstract

HIV/AIDS and schistosomiasis both cause a substantial disease burden in sub-Saharan Africa and the two diseases often overlap in their epidemiological characteristics. Although disease-specific control interventions are continuing, potential synergies in the control efforts for these two diseases have not been investigated. With a focus on children with schistosomiasis, we assess the risk for increased HIV transmission, HIV progression, and impaired response to drugs when given alongside HIV interventions. A new research agenda tailored to children is needed to better understand the interactions of these two diseases and the potential for combined responses.