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Welcome to RVC Repository

RVC Research Online is a repository of the research outputs produced by staff from the Royal Veterinary College (RVC). The aims of the repository are (i) to provide an institutional archive of RVC's research outputs, (ii) to provide access to these outputs and support open science, and (iii) to increase the reach and impact of RVC's research.



Latest Additions

Loss-of-function coding variants in the Ras of complex proteins/GTPase domain of leucine rich repeat kinase 2 (2025)
Journal Article
Butterfield, S., Herbst, S., & Lewis, P. (2025). Loss-of-function coding variants in the Ras of complex proteins/GTPase domain of leucine rich repeat kinase 2. Protein Science, 34(7), https://doi.org/10.1002/pro.70190

The LRRK2 gene is a key contributor to the genetic risk of Parkinson's disease, and a priority drug target for the disorder. Leucine Rich Repeat Kinase 2, the protein product of LRRK2, is a multidomain enzyme implicated in a range of cellular process... Read More about Loss-of-function coding variants in the Ras of complex proteins/GTPase domain of leucine rich repeat kinase 2.

Attenuated but not virulent pseudorabies virus activates porcine bone marrow-derived dendritic cells (2025)
Journal Article
Ashley, E., Fuchs, W., Klupp, B., Werling, D., Graham, S., & Edwards, J. (2025). Attenuated but not virulent pseudorabies virus activates porcine bone marrow-derived dendritic cells. Veterinary Immunology and Immunopathology, 285, https://doi.org/10.1016/j.vetimm.2025.110960

Pseudorabies viruses (PrV), the causative agent of Aujeszky's disease, continues to cause economic losses to pig producers across Southeast Asia. PrV is controlled by vaccination with live attenuated vaccines, such as the Bartha K61 strain, which has... Read More about Attenuated but not virulent pseudorabies virus activates porcine bone marrow-derived dendritic cells.

Conformational eyelid disorders in dogs under primary veterinary care in the UK - Epidemiology and clinical management (2025)
Journal Article
O'Neill, D., Mustikka, M. P., Brodbelt, D. C., Church, D. B., & Vaattovaara, V. (2025). Conformational eyelid disorders in dogs under primary veterinary care in the UK - Epidemiology and clinical management. Herpetological Conservation and Biology, 20(6), e0326526. https://doi.org/10.1371/journal.pone.0326526

Introduction Natural eyelid conformation is essential for normal function and health of the ocular surface. However, many modern dog types are deliberately bred for abnormal eyelid conformation associated with severe health and welfare issues. This s... Read More about Conformational eyelid disorders in dogs under primary veterinary care in the UK - Epidemiology and clinical management.

Synopsis of the antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID) (2025)
Journal Article
Loeffler, A., Cain, C., Ferrer, L., Nishifuji, K., Varjonen, K., Papich, M., Guardabassi, L., Frosini, S., Barker, E., & Weese, S. (2025). Synopsis of the antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID). Veterinary Dermatology, https://doi.org/10.1111/vde.13365

BackgroundCanine pyoderma is one of the most common presentations in small animal practice, frequently leading to antimicrobial prescribing.ObjectivesTo provide clinicians with antimicrobial treatment guidelines for staphylococcal pyoderma, including... Read More about Synopsis of the antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID).