Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes

Attardo, G M and Abd-Alla, A M M and Acosta-Serrano, A and Allen, J E and Bateta, R and Benoit, J B and Bourtzis, K and Caers, J and Caljon, G and Christensen, M B and Farrow, D W and Friedrich, M and Hua-Van, A and Jennings, E C and Larkin, D M and Lawson, D and Lehane, M J and Lenis, V P and Lowy-Gallego, E and Macharia, R W and Malacrida, A R and Marco, H G and Masiga, D and Maslen, G L and Matetovici, I and Meisel, R P and Meki, I and Michalkova, V and Miller, W J and Minx, P and Mireji, P O and Ometto, L and Parker, A G and Rio, R and Rose, C and Rosendale, A J and Rota-Stabelli, O and Savini, G and Schoofs, L and Scolari, F and Swain, M T and Takác, P and Tomlinson, C and Tsiamis, G and Van Den Abbeele, J and Vigneron, A and Wang, J and Warren, W C and Waterhouse, R M and Weirauch, M T and Weiss, B L and Wilson, R K and Zhao, X and Aksoy, S (2019) Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes. Genome Biology, 20. p. 187.

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Abstract

Tsetse flies (Glossina sp.) are the vectors of human and animal trypanosomiasis throughout sub-Saharan Africa. Tsetse flies are distinguished from other Diptera by unique adaptations, including lactation and the birthing of live young (obligate viviparity), a vertebrate blood-specific diet by both sexes, and obligate bacterial symbiosis. This work describes the comparative analysis of six Glossina genomes representing three sub-genera: Morsitans (G. morsitans morsitans, G. pallidipes, G. austeni), Palpalis (G. palpalis, G. fuscipes), and Fusca (G. brevipalpis) which represent different habitats, host preferences, and vectorial capacity.