Effect of varying the dose of corn syrup on the insulin and glucose response to the oral sugar test

Jocelyn, N A and Harris, P A and Menzies-Gow, N J (2018) Effect of varying the dose of corn syrup on the insulin and glucose response to the oral sugar test. EQUINE VETERINARY JOURNAL.

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Abstract

After an overnight fast, in a three‐way randomised crossover study with a 7‐day washout, 0.15, 0.3 or 0.45 mL/kg bwt corn syrup was administered orally to eight ponies (5 PL and 3 NL) and blood obtained between 0 and 120 min. Serum [insulin] and [glucose] were measured using previously validated radioimmunoassay and colorimetric assays respectively. The repeatability of and the effect of continued pasture access on the dose that best distinguished PL and NL ponies were then assessed. The effect of dose, laminitis history and fasting on serum [insulin] and [glucose] responses were assessed using mixed‐effects models.