Characterisation of a mobilisable plasmid conferring florfenicol and chloramphenicol resistance in Actinobacillus pleuropneumoniae

Bosse, J T and Li, Y and Atherton, T G and Walker, S and Williamson, S M and Rogers, J and Chaudhuri, R R and Weinert, L A and Holden, M T G and Maskell, D J and Tucker, A W and Wren, B W and Rycroft, A N and Langford, P R (2015) Characterisation of a mobilisable plasmid conferring florfenicol and chloramphenicol resistance in Actinobacillus pleuropneumoniae. VETERINARY MICROBIOLOGY, 178 (3-4). pp. 279-282.

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Abstract

The complete nucleotide sequence of a 7.7 kb mobilisable plasmid (pM3446F), isolated from a florfenicol resistant isolate of Actinobacillus pleuropneumoniae, showed extended similarity to plasmids found in other members of the Pasteurellaceae containing the floR gene as well as replication and mobilisation genes. Mobilisation into other Pasteurellaceae species confirmed that this plasmid can be transferred horizontally.